Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 1.00 |
| ▸ | RAB9A | P51151 | 11/20 | 1.00 |
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.65 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.65 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20787903 | 0.81 | NPC1 (0.74) | NPC1RAB9ALMNANPSR1HSD17B10 | |
| SCHEMBL77592 | 0.80 | SMN1; SMN2 (0.77) | NPC1RAB9ALMNANPSR1HSD17B10 | |
| SCHEMBL20769725 | 0.79 | RAB9A (0.65) | NPC1RAB9ALMNANPSR1HSD17B10 | |
| SCHEMBL704723 | 0.79 | SMN1; SMN2 (1.00) | NPC1RAB9ALMNANPSR1HSD17B10 | |
| SCHEMBL20787910 | 0.78 | NPC1 (1.00) | NPC1RAB9ALMNANPSR1HSD17B10 | |
| SCHEMBL20791856 | 0.78 | NPC1 (0.70) | NPC1RAB9ALMNANPSR1HSD17B10 | |
| SCHEMBL22728466 | 0.78 | NPC1 (0.66) | NPC1RAB9ALMNANPSR1HSD17B10 | |
| SCHEMBL20787908 | 0.78 | NPC1 (0.64) | NPC1RAB9ALMNANPSR1HSD17B10 | |
| SCHEMBL20791858 | 0.77 | SMN1; SMN2 (0.77) | NPC1RAB9ALMNANPSR1HSD17B10 | |
| SCHEMBL77958 | 0.77 | SMN1; SMN2 (0.77) | NPC1RAB9ALMNANPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8920785-B2 | Cosmetic or dermatological preparations with a content of one or more thiazole derivates | BEIERSDORF AG (DE) | 2014-12-30 | — | — | US | disclosed |
| US-8920785-B2 | Cosmetic or dermatological preparations with a content of one or more thiazole derivates | BEIERSDORF AG (DE) | 2014-12-30 | — | — | US | disclosed |
| US-20130039870-A1 | Cosmetic Or Dermatological Preparations With A Content Of One Or More Thiazole Derivates | BEIERSDORF AG (DE) | 2013-02-14 | — | — | US | disclosed |
| US-20130039870-A1 | Cosmetic Or Dermatological Preparations With A Content Of One Or More Thiazole Derivates | BEIERSDORF AG (DE) | 2013-02-14 | — | — | US | disclosed |
| WO-2011117034-A2 | COSMETIC OR DERMATOLOGICAL PREPARATIONS WITH A CONTENT OF ONE OR MORE THIAZOLE DERIVATIVES | BEIERSDORF AG (DE) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130039870-A1 | Cosmetic Or Dermatological Preparations With A Content Of One Or More Thiazole Derivates | TYR, CUTA, MITF | NPC1 693/4885RAB9A 3404/4885LMNA 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.