Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934747 | 0.89 | ADK (0.35) | SRCMEN1NR2F2KMT2AADK | |
| SCHEMBL22554085 | 0.76 | KDM4C (0.40) | MEN1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL12590784 | 0.74 | KMO (0.38) | MEN1KMT2AKDM4ENOTUMEIF2AK3 | |
| SCHEMBL6935719 | 0.74 | ADK (0.48) | SRCMEN1NR2F2KMT2AADK | |
| SCHEMBL4076506 | 0.74 | NTRK1 (0.45) | SMN1; SMN2NTRK1 | |
| SCHEMBL12984893 | 0.74 | NTRK1 (0.45) | MEN1KMT2ALMNAKDM4ENTRK1 | |
| SCHEMBL5116426 | 0.74 | RET (0.45) | SRCMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL22729832 | 0.73 | LMNA (0.45) | MEN1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL29912799 | 0.73 | LMNA (0.45) | MEN1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL13798686 | 0.73 | KMT2A (0.37) | MEN1KMT2ASMN1; SMN2KDM4EKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011018894-A1 | PYRROLOPYRIMIDINE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | RAQUALIA PHARMA INC. (JP) | 2011-02-17 | — | — | WO | disclosed |
| WO-2011018894-A1 | PYRROLOPYRIMIDINE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | RAQUALIA PHARMA INC. (JP) | 2011-02-17 | — | — | WO | disclosed |