SCHEMBL2808624

SCHEMBL2808624

O=C(O)CCCCCCC(=O)NCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.59
FAAH O00519 4/20 0.58
LMNA P02545 2/20 0.57
PMP22 Q01453 2/20 0.57
TSHR P16473 1/20 0.57
NFKB1 P19838 1/20 0.57
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
PRMT1 Q99873 1/20 0.52
EPHX2 P34913 2/20 0.51
RECQL P46063 2/20 0.50
KDM4E B2RXH2 2/20 0.49
USP2 O75604 1/20 0.49
ALDH1A1 P00352 1/20 0.49
POLB P06746 1/20 0.49
CYP3A4 P08684 1/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 1/20 0.49
ALOX15 P16050 1/20 0.49
APEX1 P27695 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6888800 1.00 PTPN1 (0.59) PTPN1FAAHLMNAPMP22TSHR
SCHEMBL12296709 1.00 PTPN1 (0.59) PTPN1FAAHLMNAPMP22TSHR
SCHEMBL13694070 1.00 PTPN1 (0.59) PTPN1FAAHLMNAPMP22TSHR
SCHEMBL22838868 1.00 PTPN1 (0.59) PTPN1FAAHLMNAPMP22TSHR
SCHEMBL20750809 1.00 PTPN1 (0.59) PTPN1FAAHLMNAPMP22TSHR
SCHEMBL24961509 1.00 PTPN1 (0.59) PTPN1FAAHLMNAPMP22TSHR
SCHEMBL7602768 1.00 PTPN1 (0.59) PTPN1FAAHLMNAPMP22TSHR
SCHEMBL15680097 0.98 PTPN1 (0.56) PTPN1FAAHLMNAPMP22TSHR
SCHEMBL8750020 0.95 PTPN1 (0.63) PTPN1FAAHLMNAPMP22TSHR
SCHEMBL10056657 0.95 PTPN1 (0.63) PTPN1FAAHLMNAPMP22TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
EP-4204100-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE L'OREAL (FR) 2023-07-05 EP disclosed
CN-116322616-A Hair lightening compositions providing damage protection and sensory benefits and methods of use 欧莱雅 2023-06-23 CN disclosed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 US disclosed
US-20220120761-A1 Urine metabolomics based method of detecting renal allograft injury THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-21 US disclosed
WO-2022047081-A1 HAIR LIGHTENING COMPOSITIONS PROVIDING DAMAGE PROTECTION AND SENSORIAL BENEFITS AND METHODS OF USE HENRY DEREK (US) 2022-03-03 WO disclosed
US-20200033361-A1 Detection and Quantitation Method for Proteomics of Post-Translational Modifications SICHUAN UNIVERSITY (CN) 2020-01-30 US disclosed
CN-108627647-A A kind of detection of posttranslational modification proteomics and quantitative approach 四川大学 2018-10-09 CN disclosed
WO-2018119500-A1 VISCOELASTIC COSMETIC COMPOSITIONS L'OREAL (FR) 2018-07-05 WO disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-7993931-B1 Oxygen-18 labeled organic acids and use in diagnosing metabolic disorders QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) 2011-08-09 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 PTPN1 1478/4885FAAH 284/4885LMNA 1561/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB PTPN1 2600/4885FAAH 2058/4885LMNA 72/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA PTPN1 1680/4885FAAH 777/4885LMNA 833/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA PTPN1 1734/4885FAAH 2263/4885LMNA 966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.