SCHEMBL12300930

SCHEMBL12300930

COc1ccc(Oc2cc(C)c(-c3csc(NC(=O)c4ccncc4)n3)c(C)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.58
ALDH1A1 P00352 3/20 0.58
THRB P10828 1/20 0.58
MAPK1 P28482 7/20 0.57
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
KDM4E B2RXH2 4/20 0.57
TSHR P16473 4/20 0.57
LMNA P02545 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
F2 P00734 1/20 0.57
ADORA3 P0DMS8 2/20 0.56
PARP1 P09874 1/20 0.52
RAB9A P51151 2/20 0.52
ROCK1 Q13464 3/20 0.51
NPC1 O15118 2/20 0.50
ROCK2 O75116 2/20 0.49
STAT3 P40763 1/20 0.49
HSD17B10 Q99714 1/20 0.49
NPSR1 Q6W5P4 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12301161 0.93 MAPT (0.53) MAPTALDH1A1THRBMAPK1MEN1
SCHEMBL15004125 0.93 MAPT (0.53) MAPTALDH1A1THRBMAPK1MEN1
SCHEMBL12248436 0.93 GCK (0.54) MAPTALDH1A1THRBMAPK1MEN1
SCHEMBL12300934 0.93 MAPT (0.63) MAPTALDH1A1THRBMAPK1MEN1
SCHEMBL14992571 0.92 PARP1 (0.60) MAPTALDH1A1THRBMAPK1MEN1
SCHEMBL12300952 0.91 MAPT (0.66) MAPTALDH1A1THRBMAPK1MEN1
SCHEMBL16523127 0.91 MAPT (0.52) MAPTALDH1A1THRBMAPK1MEN1
SCHEMBL12249093 0.91 GCK (0.56) MAPTALDH1A1THRBMAPK1MEN1
SCHEMBL12249080 0.91 PARP1 (0.61) MAPTALDH1A1THRBMAPK1TSHR
SCHEMBL12300955 0.90 MAPT (0.51) MAPTALDH1A1THRBMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120123621-A Reservoir water temperature estimation method, system and storage medium 国能大渡河瀑布沟发电有限公司 2025-06-10 CN claimed
CN-116109571-B Automatic fiber bundle reconstruction method and system for facial auditory nerve 浙江大学 2024-04-26 CN claimed
CN-114285055-B Intelligent power supply management method combining wind-solar power generation 金名正元(北京)科技有限公司 2022-06-17 CN claimed
CN-114421558-A Intelligent power supply management method 金名正元(北京)科技有限公司 2022-04-29 CN claimed
CN-114285055-A Intelligent power supply management method combining wind-solar power generation 金名正元(北京)科技有限公司 2022-04-05 CN claimed
EP-2783217-B1 BIOMARKERS FOR CANCERS RESPONSIVE TO MODULATORS OF HEC1 ACTIVITY TAIVEX THERAPEUTICS CORP (TW) 2019-04-24 EP claimed
US-9976183-B2 Biomarkers for cancers responsive to modulators of HEC1 activity TAIVEX THERAPEUTICS CORPORATION (TW) 2018-05-22 US claimed
EP-2783217-A1 BIOMARKERS FOR CANCERS RESPONSIVE TO MODULATORS OF HEC1 ACTIVITY Taivex Therapeutics Corporation (TW) 2014-10-01 EP claimed
US-20130171634-A1 BIOMARKERS FOR CANCERS RESPONSIVE TO MODULATORS OF HEC1 ACTIVITY TAIVEX THERAPEUTICS CORPORATION (TW) 2013-07-04 US claimed
WO-2013078145-A1 BIOMARKERS FOR CANCERS RESPONSIVE TO MODULATORS OF HEC1 ACTIVITY TAIVEX THERAPEUTICS CORPORATION (TW) 2013-05-30 WO claimed
US-12641132-B2 Methods and apparatuses for selecting a media resource function or a media gateway in an internet protocol session TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) (SE) 2026-05-26 US disclosed
EP-4744386-A1 METHOD AND APPARATUS FOR HANDLING OF NETWORK SLICE SELECTION ASSISTANCE INFORMATION LISTS IN A WIRELESS COMMUNICATION SYSTEM Samsung Electronics Co., Ltd. (KR) 2026-05-20 EP disclosed
CN-119844892-B Method and device for controlling rotating speed of variable frequency compressor of air conditioner 青岛海尔智慧楼宇科技有限公司 2026-05-19 CN disclosed
WO-2026101177-A1 HANDLING CELL SELECTION OR RESELECTION OF A CELL ASSOCIATED WITH A TAI IN A WIRELESS COMMUNICATION SYSTEM SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-05-15 WO disclosed
US-12627951-B2 Fifth generation core enhancements to support ad hoc and dynamic group based services for edge deployments NOKIA TECHNOLOGIES OY (FI) 2026-05-12 US disclosed
US-20130171634-A1 BIOMARKERS FOR CANCERS RESPONSIVE TO MODULATORS OF HEC1 ACTIVITY TAIVEX THERAPEUTICS CORPORATION (TW) 2013-07-04 US disclosed
WO-2013082324-A1 IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR TAIVEX THERAPEUTICS CORPORATION (TW) 2013-06-06 WO disclosed
WO-2013082324-A1 IMPROVED MODULATORS OF HEC1 ACTIVITY AND METHODS THEREFOR TAIVEX THERAPEUTICS CORPORATION (TW) 2013-06-06 WO disclosed
WO-2013078145-A1 BIOMARKERS FOR CANCERS RESPONSIVE TO MODULATORS OF HEC1 ACTIVITY TAIVEX THERAPEUTICS CORPORATION (TW) 2013-05-30 WO disclosed
US-20110230486-A1 Modulators Of HEC1 Activity And Methods Therefor TAIVEX THERAPEUTICS CORPORATION (TW) 2011-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12627951-B2 Fifth generation core enhancements to support ad hoc and dynamic group based services for edge deployments HTR3E, NT5M, HTR5A MAPT 153/4885ALDH1A1 1752/4885THRB 250/4885
US-12641132-B2 Methods and apparatuses for selecting a media resource function or a media gateway in an internet protocol session SARAF, PLA2G2F, PRPF8 MAPT 2538/4885ALDH1A1 4464/4885THRB 4031/4885
US-20110230486-A1 Modulators Of HEC1 Activity And Methods Therefor WEE1, WEE2, NEK11 MAPT 2820/4885ALDH1A1 3229/4885THRB 3699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.