⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302009 | 0.92 | — | — | |
| SCHEMBL12302014 | 0.88 | HTR7 (0.32) | — | |
| SCHEMBL20885373 | 0.86 | MAPT (0.34) | — | |
| SCHEMBL12301932 | 0.83 | HTR1A (0.30) | — | |
| SCHEMBL15219002 | 0.83 | NPC1 (0.30) | — | |
| SCHEMBL12302006 | 0.83 | ADRB2 (0.31) | — | |
| SCHEMBL18634110 | 0.81 | TYMS (0.30) | — | |
| SCHEMBL14982693 | 0.80 | INSR (0.36) | — | |
| SCHEMBL2544507 | 0.78 | SNCA (0.35) | — | |
| SCHEMBL20885372 | 0.78 | INSR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9366676-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150316558-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | MOLECULAR PROBES, INC. | 2015-11-05 | — | — | US | disclosed |
| US-9115397-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2015-08-25 | — | — | US | disclosed |
| US-20150004597-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | LIFE TECHNOLOGIES CORP (US) | 2015-01-01 | — | — | US | disclosed |
| US-8865904-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2014-10-21 | — | — | US | disclosed |
| US-20130224735-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2013-08-29 | — | — | US | disclosed |
| US-20120288855-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2012-11-15 | — | — | US | disclosed |
| US-20110217699-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2011-09-08 | — | — | US | disclosed |
| US-7943777-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2011-05-17 | — | — | US | disclosed |
| US-20100143917-A1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | Life Technologies Corporation (US) | 2010-06-10 | — | — | US | disclosed |
| US-7598390-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2009-10-06 | — | — | US | disclosed |