Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302006 | 0.91 | ADRB2 (0.31) | NPC1POLBGAAMAPTNR2F2 | |
| SCHEMBL18634110 | 0.88 | TYMS (0.30) | — | |
| SCHEMBL16386561 | 0.83 | RORC (0.33) | — | |
| SCHEMBL12302010 | 0.83 | — | — | |
| SCHEMBL12301931 | 0.80 | RORC (0.31) | — | |
| SCHEMBL12302009 | 0.80 | — | — | |
| SCHEMBL12302004 | 0.80 | ALDH1A1 (0.31) | NPC1POLBMAPTHTTRAD52 | |
| SCHEMBL15219003 | 0.78 | BACE1 (0.32) | — | |
| SCHEMBL18634026 | 0.77 | INSR (0.30) | — | |
| SCHEMBL12302016 | 0.76 | KDM4E (0.32) | NPC1POLBMAPTHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885718-B1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | LIFE TECHNOLOGIES CORP (US) | 2017-03-15 | — | — | EP | disclosed |
| US-8865904-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2014-10-21 | — | — | US | disclosed |
| US-20130224735-A1 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use | Life Technologies Corporation (US) | 2013-08-29 | — | — | US | disclosed |