SCHEMBL1230271

SCHEMBL1230271

N=C(S)NCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 3/20 0.56
ALDH1A1 P00352 3/20 0.56
HPGD P15428 1/20 0.56
MAPT P10636 3/20 0.54
GAA P10253 3/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
POLB P06746 1/20 0.54
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
IDO1 P14902 2/20 0.50
THRB P10828 1/20 0.50
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
LMNA P02545 1/20 0.48
PKM P14618 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4003812 0.98 ALOX12 (0.54) ALOX12ALDH1A1HPGDMAPTGAA
SCHEMBL2811627 0.84 ALDH1A1 (0.52) ALOX12ALDH1A1HPGDMAPTKMT2A
Bromide SCHEMBL2811699 0.83 ALDH1A1 (0.50) ALOX12ALDH1A1HPGDMAPTKMT2A
SCHEMBL1273847 0.81 ALDH1A1 (0.60) ALOX12ALDH1A1HPGDMAPTGAA
SCHEMBL12181478 0.79 ALDH1A1 (0.54) ALOX12ALDH1A1HPGDMAPTGAA
SCHEMBL10455844 0.79 ALOX12 (0.58) ALOX12ALDH1A1HPGDMAPTGAA
SCHEMBL2813865 0.79 NPC1 (0.41) ALDH1A1HPGDMAPTKMT2AMEN1
SCHEMBL5064965 0.78 MEN1 (0.59) ALOX12ALDH1A1HPGDMAPTGAA
SCHEMBL10426536 0.78 TGM2 (0.50) ALDH1A1MAPTGAAKMT2AMEN1
SCHEMBL5339441 0.78 CA12 (0.41) ALOX12ALDH1A1HPGDMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109312318-A Be saccharified reaction solution, saccharification enzymatic compositions, the manufacturing method of sugar and the manufacturing method of ethyl alcohol 日产化学株式会社 2019-02-05 CN claimed
CN-108529732-A A method of based on ionic liquid high-efficient purification iron protein waste water 河南师范大学 2018-09-14 CN claimed
WO-2012063115-A2 PROCESS FOR THE PREPARATION OF ROSUVASTATIN CALCIUM VIA NOVEL AMINE INTERMEDIATE JUBILANT LIFE SCIENCES LTD. (IN) 2012-05-18 WO claimed
EP-2294058-A1 2-(BENZYLSULFONYL)-OXAZOLE DERIVATIVES, CHIRAL 2- (BENZYLSULFINYL) -OXAZOLE DERIVATIVES AND 2-(BENZYLSULFANYL)-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS Bayer CropScience AG (DE) 2011-03-16 EP claimed
CN-101622227-A Biaryl and biheteroaryl compounds useful in treating iron disorders XENON PHARMACEUTICALS INC 2010-01-06 CN claimed
WO-2009129953-A1 2-(BENZYLSULFONYL)-OXAZOLE DERIVATIVES, CHIRAL 2- (BENZYLSULFINYL) -OXAZOLE DERIVATIVES AND 2-(BENZYLSULFANYL)-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2009-10-29 WO claimed
EP-0897998-B1 Reductive nickel bath AMI DODUCO GMBH (DE) 2001-12-05 EP claimed
EP-0670720-A1 ENZYME INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1995-09-13 EP claimed
CN-1095710-A Enzyme Inhibitors WELLCOME FOUND (GB) 1994-11-30 CN claimed
WO-1994012165-A2 ENZYME INHIBITORS THE WELLCOME FOUNDATION LIMITED (GB) 1994-06-09 WO claimed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
CN-113201245-B Active energy ray-curable ink for offset lithography and printed matter DIC油墨株式会社 2023-11-28 CN disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
CN-116063208-A Synthesis method of difluoromethane sulfonyl chloride 安徽省化工研究院 2023-05-05 CN disclosed
US-4499303-A Antihyperlipidemic N-benzoylsulfamates, N-benzylsulfamates and benzylsulfonamides RESEARCH CORPORATION (US) 1985-02-12 US disclosed
EP-0109955-A2 Rubber/metal composites MONSANTO EUROPE S.A./N.V. (BE) 1984-05-30 EP disclosed
US-4417012-A DIENE RUBBER MONSANTO EUROPE S.A. (BE) 1983-11-22 US disclosed
EP-0070143-A1 Organic thiosulphates and thiosulphonates useful as stabilising agents for rubber vulcanisates MONSANTO EUROPE S.A./N.V. (BE) 1983-01-19 EP disclosed
US-4021461-A INSECTICIDES ZOECON CORPORATION (US) 1977-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 ALOX12 357/4885ALDH1A1 72/4885HPGD 188/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 ALOX12 357/4885ALDH1A1 72/4885HPGD 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.