Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064965 | 0.79 | MEN1 (0.59) | MEN1KMT2AALOX12POLBGAA | |
| SCHEMBL18401332 | 0.79 | CYP2C9 (0.41) | CA12CA1CA2CA7MEN1 | |
| SCHEMBL10426536 | 0.79 | TGM2 (0.50) | CA12CA1CA2CA7MEN1 | |
| SCHEMBL1230271 | 0.78 | ALOX12 (0.56) | CA12CA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4799470 | 0.78 | MEN1 (0.57) | MEN1KMT2AALOX12POLBGAA | |
| Hydrochloric Acid SCHEMBL4798435 | 0.78 | NPC1 (0.53) | MEN1KMT2APOLBGAAMAPT | |
| Hydrochloric Acid SCHEMBL4003812 | 0.77 | ALOX12 (0.54) | CA12CA1CA2MEN1KMT2A | |
| SCHEMBL5793985 | 0.75 | ALDH1A1 (0.62) | MEN1KMT2AALOX12POLBMAPT | |
| SCHEMBL850732 | 0.75 | LOXL2 (0.55) | CA12CA1CA2CA7MEN1 | |
| Hydrochloric Acid SCHEMBL10951495 | 0.73 | HTT (0.49) | GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075177-A2 | ANTIBIOTICS TARGETING MREB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-07-05 | — | — | WO | disclosed |