Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 2/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2416620 | 0.87 | GABRA1 (0.47) | LPAR1LPAR5GABRA1GABRB2OXTR | |
| SCHEMBL2416622 | 0.81 | GABRA1 (0.45) | LPAR1LPAR5GABRA1GABRB2HPGD | |
| SCHEMBL2410446 | 0.79 | RAB9A (0.51) | LPAR1GABRA1GABRB2HPGD | |
| SCHEMBL2410847 | 0.78 | GABRA1 (0.52) | GABRA1GABRB2HPGD | |
| SCHEMBL4601459 | 0.76 | TSHR (0.60) | — | |
| SCHEMBL2412849 | 0.76 | HPGD (0.56) | GABRA1GABRB2HPGD | |
| SCHEMBL14015153 | 0.74 | GABRA1 (0.49) | GABRA1GABRB2HPGD | |
| SCHEMBL2408990 | 0.73 | HPGD (0.56) | GABRA1GABRB2HPGD | |
| SCHEMBL2410449 | 0.73 | RAB9A (0.49) | GABRA1GABRB2HPGD | |
| SCHEMBL2414417 | 0.72 | HPGD (0.52) | LPAR1GABRA1GABRB2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |