Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412850 | 0.89 | HPGD (0.53) | GABRA1GABRB2USP2ALDH1A1TSHR | |
| SCHEMBL2410849 | 0.87 | GABRA1 (0.49) | GABRA1GABRB2USP2ALDH1A1TSHR | |
| SCHEMBL2413110 | 0.87 | GABRA1 (0.47) | GABRA1GABRB2USP2ALDH1A1TSHR | |
| SCHEMBL2416620 | 0.86 | GABRA1 (0.47) | GABRA1GABRB2USP2ALDH1A1TSHR | |
| SCHEMBL2410449 | 0.86 | RAB9A (0.49) | GABRA1GABRB2ALDH1A1HPGD | |
| SCHEMBL2414418 | 0.85 | HPGD (0.49) | GABRA1GABRB2USP2ALDH1A1TSHR | |
| SCHEMBL2408993 | 0.84 | HPGD (0.53) | GABRA1GABRB2ALDH1A1HPGD | |
| SCHEMBL2413426 | 0.84 | NPC1 (0.46) | GABRA1GABRB2USP2ALDH1A1TSHR | |
| SCHEMBL12320058 | 0.81 | LPAR1 (0.51) | GABRA1GABRB2HPGDLPAR1LPAR5 | |
| SCHEMBL2414935 | 0.75 | LTB4R2 (0.42) | ALDH1A1HDAC1HDAC6LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |