Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12017975 | 0.82 | IDO1 (0.61) | IDO1FFAR1 | |
| SCHEMBL12320928 | 0.80 | IDO1 (0.54) | IDO1FFAR1 | |
| SCHEMBL8529487 | 0.80 | IDO1 (0.54) | IDO1FFAR1 | |
| SCHEMBL21142124 | 0.80 | IDO1 (0.54) | IDO1FFAR1 | |
| SCHEMBL21142126 | 0.79 | IDO1 (0.50) | IDO1FFAR1 | |
| SCHEMBL12320182 | 0.78 | IDO1 (0.43) | IDO1FFAR1LRRK2TRPC6 | |
| SCHEMBL12320212 | 0.78 | IDO1 (0.43) | IDO1LRRK2TRPC6ALDH1A1LMNA | |
| SCHEMBL12320188 | 0.78 | TRPC6 (0.50) | IDO1LRRK2TRPC6 | |
| SCHEMBL12320216 | 0.78 | PGR (0.47) | IDO1FFAR1LRRK2 | |
| SCHEMBL12320193 | 0.77 | IDO1 (0.45) | IDO1FFAR1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | disclosed |