Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835040 | 0.74 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL28187002 | 0.74 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL548585 | 0.74 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL1230678 | 0.74 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL4121119 | 0.70 | — | — | |
| SCHEMBL2292112 | 0.70 | — | — | |
| SCHEMBL21399964 | 0.70 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL548602 | 0.69 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL16442717 | 0.69 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL21399816 | 0.67 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106966908-B | Process for improving the catalytic activity of catalyst systems for reductive amination of aliphatic cyanoaldehydes to aliphatic diamines | 陶氏环球技术有限责任公司 | 2020-07-31 | — | — | CN | disclosed |
| EP-2459514-B1 | CYCLOALIPHATIC DIAMINES AND METHOD OF MAKING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-07-19 | — | — | EP | disclosed |
| US-9233908-B2 | Cycloaliphatic diamines and method of making the same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-01-12 | — | — | US | disclosed |
| EP-2488482-B1 | PROCESS FOR IMPROVING THE CATALYTIC ACTIVITY OF CATALYST SYSTEMS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-2459515-B1 | PROCESS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| US-9024072-B2 | Process for reductive amination of aliphatic cyanoaldehydes to aliphatic diamines | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-05-05 | — | — | US | disclosed |
| EP-2488482-A1 | PROCESS FOR IMPROVING THE CATALYTIC ACTIVITY OF CATALYST SYSTEMS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES | Dow Global Technologies LLC (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2012087266-A1 | PROCESS FOR IMPROVING THE CATALYTIC ACTIVITY OF CATALYST SYSTEMS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| EP-2459515-A2 | PROCESS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES | Dow Global Technologies LLC (US) | 2012-06-06 | — | — | EP | disclosed |
| EP-2459514-A2 | CYCLOALIPHATIC DIAMINES AND METHOD OF MAKING THE SAME | Dow Global Technologies LLC (US) | 2012-06-06 | — | — | EP | disclosed |
| US-20120136173-A1 | PROCESS FOR IMPROVING THE CATALYTIC ACTIVITY OF CATALYST SYSTEMS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-05-31 | — | — | US | disclosed |
| US-20120123165-A1 | CYCLOALIPHATIC DIAMINES AND METHOD OF MAKING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120116124-A1 | PROCESS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-05-10 | — | — | US | disclosed |
| WO-2011014747-A2 | CYCLOALIPHATIC DIAMINES AND METHOD OF MAKING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-02-03 | — | — | WO | disclosed |
| WO-2011014787-A2 | PROCESS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123165-A1 | CYCLOALIPHATIC DIAMINES AND METHOD OF MAKING THE SAME | DDC, DDT, DNPEP | ALDH1A1 1825/4885 |
| US-20120136173-A1 | PROCESS FOR IMPROVING THE CATALYTIC ACTIVITY OF CATALYST SYSTEMS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES | DDC, ASNS, NAAA | ALDH1A1 200/4885 |
| US-20120116124-A1 | PROCESS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES | ARG1, DDC, ACMSD | ALDH1A1 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.