Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334679 | 0.92 | RAB9A (0.56) | RAB9AMAPTGAANPSR1HSD11B1 | |
| SCHEMBL12334246 | 0.86 | RAB9A (0.61) | RAB9AMAPTGAANPSR1HSD11B1 | |
| SCHEMBL12334671 | 0.85 | TRPV1 (0.46) | RAB9AMAPTGAANPSR1HSD11B1 | |
| SCHEMBL12334266 | 0.84 | HPGD (0.60) | RAB9AMAPTGAANPSR1HSD11B1 | |
| SCHEMBL19180948 | 0.80 | PDK1 (0.54) | RAB9AMAPTNPSR1HSD11B1TRPV1 | |
| SCHEMBL20956394 | 0.80 | PDK1 (0.54) | RAB9AMAPTNPSR1HSD11B1TRPV1 | |
| SCHEMBL3419156 | 0.80 | PDK1 (0.54) | RAB9AMAPTNPSR1HSD11B1TRPV1 | |
| SCHEMBL12334262 | 0.78 | TRPV1 (0.74) | RAB9AMAPTNPSR1TRPV1NPC1 | |
| SCHEMBL21047664 | 0.77 | SMN1; SMN2 (0.72) | RAB9AMAPTHSD11B1PDK1PDK2 | |
| SCHEMBL12334059 | 0.76 | MEN1 (0.67) | RAB9AMAPTNPC1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011115892-A1 | MODULATORS OF THE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTORS | GRIFFIN PATRICK R (US) | 2011-09-22 | — | — | WO | disclosed |