Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | IL2 | P60568 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334246 | 0.92 | RAB9A (0.61) | RAB9AMAPTGAANPSR1MEN1 | |
| SCHEMBL12334247 | 0.92 | RAB9A (0.48) | RAB9AMAPTGAANPSR1MEN1 | |
| SCHEMBL21629913 | 0.81 | MEN1 (0.57) | RAB9AMAPTGAANPSR1MEN1 | |
| SCHEMBL12334266 | 0.80 | HPGD (0.60) | RAB9AMAPTGAANPSR1MEN1 | |
| SCHEMBL12334059 | 0.80 | MEN1 (0.67) | RAB9AMAPTMEN1KMT2AHTT | |
| SCHEMBL16017296 | 0.79 | RAB9A (0.53) | RAB9AMAPTGAANPSR1MEN1 | |
| SCHEMBL16583943 | 0.79 | GAA (0.59) | RAB9AMAPTGAANPSR1MEN1 | |
| SCHEMBL15205641 | 0.78 | MEN1 (0.55) | RAB9AMAPTGAANPSR1MEN1 | |
| SCHEMBL12334582 | 0.78 | RORC (0.61) | RAB9AMAPTGAANPSR1MEN1 | |
| SCHEMBL12334671 | 0.78 | TRPV1 (0.46) | RAB9AMAPTGAANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011115892-A1 | MODULATORS OF THE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTORS | GRIFFIN PATRICK R (US) | 2011-09-22 | — | — | WO | disclosed |