Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334628 | 0.90 | GPR27 (0.58) | NPC1RAB9AGPR27ALDH1A1LMNA | |
| SCHEMBL12334253 | 0.88 | MEN1 (0.47) | KMT2AHSD11B1 | |
| SCHEMBL12334579 | 0.86 | SNCA (0.59) | SNCANPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL12334059 | 0.84 | MEN1 (0.67) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL7079567 | 0.77 | SNCA (0.58) | SNCANPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL12334244 | 0.77 | TRPV1 (0.50) | NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL12334246 | 0.77 | RAB9A (0.61) | NPC1RAB9AMAPTLMNAGAA | |
| SCHEMBL6544730 | 0.76 | SNCA (0.62) | SNCANPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL27964618 | 0.76 | SNCA (0.67) | SNCANPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL677811 | 0.76 | SNCA (0.67) | SNCANPC1RAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011115892-A1 | MODULATORS OF THE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTORS | GRIFFIN PATRICK R (US) | 2011-09-22 | — | — | WO | disclosed |