Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334252 | 0.88 | SNCA (0.56) | KMT2AHSD11B1 | |
| SCHEMBL12334244 | 0.86 | TRPV1 (0.50) | TRPV1KIT | |
| SCHEMBL12334266 | 0.83 | HPGD (0.60) | MEN1KMT2AHSD11B1 | |
| SCHEMBL12334628 | 0.81 | GPR27 (0.58) | KMT2ATRPV1 | |
| SCHEMBL12334059 | 0.77 | MEN1 (0.67) | MEN1KMT2A | |
| SCHEMBL12334262 | 0.76 | TRPV1 (0.74) | MEN1KMT2ATRPV1 | |
| SCHEMBL12334247 | 0.76 | RAB9A (0.48) | MEN1KMT2AHSD11B1TRPV1 | |
| SCHEMBL20956394 | 0.76 | PDK1 (0.54) | MEN1KMT2AHSD11B1TRPV1 | |
| SCHEMBL3419156 | 0.76 | PDK1 (0.54) | MEN1KMT2AHSD11B1TRPV1 | |
| SCHEMBL19180948 | 0.76 | PDK1 (0.54) | MEN1KMT2AHSD11B1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011115892-A1 | MODULATORS OF THE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTORS | GRIFFIN PATRICK R (US) | 2011-09-22 | — | — | WO | disclosed |