Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | XIAP | P98170 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BIRC2 | Q13490 | 5/20 | 0.43 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12780144 | 0.85 | ELANE (0.46) | ELANECYP3A4XIAPCYP2C9CYP2C19 | |
| SCHEMBL24051779 | 0.79 | ELANE (0.42) | ELANECYP3A4XIAPCYP2C9CYP2C19 | |
| SCHEMBL14421202 | 0.78 | ELANE (0.42) | ELANECYP3A4XIAPCYP2C9CYP2C19 | |
| SCHEMBL14421210 | 0.76 | XIAP (0.49) | ELANECYP3A4XIAPCYP2C9CYP2C19 | |
| SCHEMBL160496 | 0.76 | XIAP (0.49) | ELANECYP3A4XIAPCYP2C9CYP2C19 | |
| SCHEMBL15705223 | 0.76 | XIAP (0.49) | ELANECYP3A4XIAPCYP2C9CYP2C19 | |
| SCHEMBL160497 | 0.76 | XIAP (0.49) | ELANECYP3A4XIAPCYP2C9CYP2C19 | |
| SCHEMBL17188760 | 0.75 | UCHL1 (0.46) | ELANEMEN1KMT2AHTR1AHTR7 | |
| SCHEMBL7943694 | 0.75 | ELANE (0.46) | ELANERAB9A | |
| Hydrochloric Acid SCHEMBL156848 | 0.75 | XIAP (0.49) | ELANECYP3A4XIAPCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505963-B9 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-21 | — | — | EP | disclosed |