Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | STAT6 | P42226 | 4/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12336180 | 0.85 | ELANE (0.46) | ELANEHTR1AHTR7CYP3A4CYP2C9 | |
| SCHEMBL8274139 | 0.79 | ELANE (0.40) | ELANESTAT6 | |
| SCHEMBL8133784 | 0.79 | ELANE (0.40) | ELANESTAT6 | |
| SCHEMBL13960895 | 0.79 | ELANE (0.40) | ELANESTAT6 | |
| SCHEMBL806180 | 0.79 | ELANE (0.42) | ELANE | |
| SCHEMBL8055611 | 0.79 | ELANE (0.42) | ELANE | |
| SCHEMBL14232792 | 0.79 | ELANE (0.42) | ELANE | |
| SCHEMBL8145204 | 0.78 | ELANE (0.43) | ELANESTAT6XIAP | |
| SCHEMBL17188760 | 0.78 | UCHL1 (0.46) | ELANEHTR1AHTR7 | |
| SCHEMBL7943694 | 0.77 | ELANE (0.46) | ELANESTAT6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505963-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-04-20 | — | — | EP | disclosed |