Sugi Predict

Sugi Predict / Compounds / SCHEMBL1234231

SCHEMBL1234231

SCHEMBL1234231

NCCNCCN[C@@H](CC(=O)O)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.39
▸ CA12 O43570 3/20 0.39
▸ CA6 P23280 3/20 0.39
▸ CA7 P43166 3/20 0.39
▸ CA9 Q16790 3/20 0.39
▸ CA14 Q9ULX7 3/20 0.39
▸ CA5B Q9Y2D0 3/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA3 P07451 2/20 0.39
▸ CA4 P22748 2/20 0.39
▸ CA5A P35218 2/20 0.39
▸ CA1 P00915 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ GGT1 P19440 1/20 0.38
▸ KMT2A Q03164 2/20 0.36
▸ MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19412149 1.00 LMNA (0.39) LMNACA12CA6CA7CA9
SCHEMBL19209890 1.00 LMNA (0.39) LMNACA12CA6CA7CA9
Hydrochloric Acid SCHEMBL9905495 0.98 KDM4E (0.41) LMNACA12CA6CA7CA9
SCHEMBL27902177 0.89 GGT1 (0.46) LMNACA2CA4GGT1GABRR1
SCHEMBL30436578 0.87 GGT1 (0.46) LMNACA12CA6CA7CA9
SCHEMBL30437177 0.87 GGT1 (0.46) LMNACA12CA6CA7CA9
SCHEMBL7860275 0.87 GGT1 (0.46) LMNACA12CA6CA7CA9
SCHEMBL30370036 0.87 GGT1 (0.46) LMNACA12CA6CA7CA9
SCHEMBL30437179 0.87 GGT1 (0.46) LMNACA12CA6CA7CA9
SCHEMBL9905502 0.87 CA12 (0.41) LMNACA12CA6CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3352795-B1 COMPOSITIONS AND METHODS FOR TARGET NUCLEIC ACID MODIFICATION UNIV CALIFORNIA (US) 2020-08-12 — — EP claimed
US-20200017852-A1 COMPOSITIONS AND METHODS FOR TARGET NUCLEIC ACID MODIFICATION GENEDIT INC. 2020-01-16 — — US claimed
US-10071055-B2 Reducing or non-reducing polynucleotide polymer for drug delivery and method for preparing same THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2018-09-11 — — US claimed
US-20180237800-A1 COMPOSITIONS AND METHODS FOR TARGET NUCLEIC ACID MODIFICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-08-23 — — US claimed
US-20160193150-A1 REDUCING OR NON-REDUCING POLYNUCLEOTIDE POLYMER FOR DRUG DELIVERY AND METHOD FOR PREPARING SAME THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2016-07-07 — — US claimed
EP-3012263-A1 REDUCING OR NON-REDUCING POLYNUCLEOTIDE POLYMER FOR DRUG DELIVERY AND METHOD FOR PREPARING SAME The Catholic University of Korea Industry-Academic Cooperation Foundation (KR) 2016-04-27 — — EP claimed
WO-2024063538-A1 BASE EDITING OF PLANT CELL ORGANELLE DNA 기초과학연구원 2024-03-28 — — WO disclosed
US-20240093243-A1 METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELL BY USING CRISPR/CAS SYSTEM AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2024-03-21 — — US disclosed
US-20240075148-A1 POLY-ION COMPLEX MICELLE KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION (JP) 2024-03-07 — — US disclosed
US-20240018492-A1 PRIME EDITING USING HIV REVERSE TRANSCRIPTASE AND CAS9 OR VARIANT THEREOF INSTITUTE FOR BASIC SCIENCE (KR) 2024-01-18 — — US disclosed
WO-2023182858-A1 ADENINE-TO-GUANINE BASE EDITING METHOD OF PLANT CELL ORGANELLE DNA 기초과학연구원 2023-09-28 — — WO disclosed
EP-4215608-A1 TARGETED DEAMINASE AND BASE EDITING USING SAME Institute for Basic Science (KR) 2023-07-26 — — EP disclosed
US-20230151343-A1 GENOME EDITING USING CAS9 OR CAS9 VARIANT INSTITUTE FOR BASIC SCIENCE (KR) 2023-05-18 — — US disclosed
WO-2016097377-A1 COMPOSITIONS FOR INTRODUCING NUCLEIC ACID INTO CELLS ETHRIS GMBH (DE) 2016-06-23 — — WO disclosed
EP-3034539-A1 Compositions for introducing nucleic acid into cells Ethris GmbH (DE) 2016-06-22 — — EP disclosed
EP-3012263-A1 REDUCING OR NON-REDUCING POLYNUCLEOTIDE POLYMER FOR DRUG DELIVERY AND METHOD FOR PREPARING SAME The Catholic University of Korea Industry-Academic Cooperation Foundation (KR) 2016-04-27 — — EP disclosed
US-9303122-B2 Charge conversional ternary polyplex THE UNIVERSITY OF TOKYO (JP) 2016-04-05 — — US disclosed
US-20150141575-A1 CHARGE CONVERSIONAL TERNARY POLYPLEX THE UNIVERSITY OF TOKYO (JP) 2015-05-21 — — US disclosed
US-20110060123-A1 CHARGE CONVERSIONAL TERNARY POLYPLEX THE UNIVERSITY OF TOKYO (JP) 2011-03-10 — — US disclosed
EP-2284210-A1 CHARGE CONVERSIONAL TERNARY POLYPLEX The University of Tokyo (JP) 2011-02-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110060123-A1 CHARGE CONVERSIONAL TERNARY POLYPLEX PARN, PARG, NCAPD2 LMNA 299/4885CA12 517/4885CA6 118/4885
US-20160193150-A1 REDUCING OR NON-REDUCING POLYNUCLEOTIDE POLYMER FOR DRUG DELIVERY AND METHOD FOR PREPARING SAME PHAX, PCNP, NUP205 LMNA 1281/4885CA12 4456/4885CA6 3085/4885
US-20240075148-A1 POLY-ION COMPLEX MICELLE CLTB, KCNMB1, CHMP4B LMNA 700/4885CA12 113/4885CA6 1571/4885
US-10071055-B2 Reducing or non-reducing polynucleotide polymer for drug delivery and method for preparing same PHAX, NSF, NUDT1 LMNA 1833/4885CA12 4385/4885CA6 3397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.