Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.37 |
| ▸ | CNR1 | P21554 | 13/20 | 0.37 |
| ▸ | GPR18 | Q14330 | 3/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235880 | 0.80 | CNR2 (0.37) | CNR2CNR1TLR8ALDH1A1 | |
| SCHEMBL1234705 | 0.68 | CNR1 (0.53) | CNR2CNR1GPR55ALDH1A1 | |
| SCHEMBL1264587 | 0.66 | CNR1 (0.44) | CNR2CNR1GPR18GPR55 | |
| SCHEMBL1193053 | 0.65 | ALDH1A1 (0.33) | CNR2CNR1TLR8ALDH1A1RXFP1 | |
| SCHEMBL1491145 | 0.64 | CNR2 (0.46) | CNR2CNR1GPR18GPR55 | |
| SCHEMBL12895418 | 0.64 | CNR2 (0.47) | CNR2CNR1GPR18GPR55 | |
| SCHEMBL1235869 | 0.63 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL1491142 | 0.63 | CNR1 (0.44) | CNR2CNR1 | |
| SCHEMBL1491146 | 0.62 | CNR2 (0.46) | CNR2CNR1GPR18GPR55ALDH1A1 | |
| Heptane SCHEMBL8571539 | 0.62 | KDM4E (0.50) | TLR8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | claimed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | claimed |
| WO-2011022679-A2 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | claimed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476309-B2 | Benzofuran cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| WO-2011022679-A2 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046175-A1 | BENZOFURAN CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, GPR18 | CNR2 2/4885CNR1 1/4885GPR18 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.