Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349572 | 0.73 | ALDH1A1 (0.83) | ALDH1A1MAPTKDM4ECYP1A2GAA | |
| SCHEMBL7571452 | 0.69 | HRH3 (0.50) | ALDH1A1KDM4ECYP1A2CYP1A1CYP1B1 | |
| SCHEMBL11179647 | 0.68 | RXFP1 (0.46) | ALDH1A1MAPTKDM4ECYP1A2GAA | |
| SCHEMBL9006419 | 0.68 | XDH (0.49) | ALDH1A1MAPTKDM4ECYP1A2GAA | |
| SCHEMBL9533817 | 0.68 | TNKS (0.43) | ALDH1A1KDM4ECYP1A2CYP1A1CYP1B1 | |
| SCHEMBL8128430 | 0.67 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ECYP1A2GAA | |
| SCHEMBL9534241 | 0.67 | PKM (0.50) | ALDH1A1MAPTKDM4ECYP1A2CYP1A1 | |
| SCHEMBL11181520 | 0.66 | CYP2C19 (0.49) | ALDH1A1MAPTKDM4ECYP1A2GAA | |
| SCHEMBL10695759 | 0.66 | CYP1A1 (0.43) | ALDH1A1KDM4ECYP1A2CYP1A1CYP1B1 | |
| SCHEMBL9536686 | 0.66 | KDM4E (0.59) | ALDH1A1MAPTKDM4ECYP1A2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-B1 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |