Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349852 | 0.70 | POLB (1.00) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL30567461 | 0.70 | POLB (1.00) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL15440670 | 0.64 | POLB (0.60) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL10799708 | 0.61 | POLB (0.55) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL13467765 | 0.61 | POLB (0.65) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL10979328 | 0.61 | SMN1; SMN2 (0.50) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL15440804 | 0.61 | HTT (0.67) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL11837490 | 0.60 | HSD17B10 (0.56) | POLBNPC1MITFDNMT1HTT | |
| SCHEMBL929729 | 0.60 | MAOB (0.77) | POLBKMT2AMAOBACHEBCHE | |
| SCHEMBL9464811 | 0.59 | POLB (0.47) | POLBNPC1MITFDNMT1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094693-A1 | INTERFERON-INDUCING COMPOUNDS AND USES THEREOF | MOUNT SINAI SCHOOL OF MEDICINE (US) | 2011-08-04 | — | — | WO | disclosed |