Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | MITF | O75030 | 1/20 | 1.00 |
| ▸ | DNMT1 | P26358 | 1/20 | 1.00 |
| ▸ | RAD52 | P43351 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567461 | 1.00 | POLB (1.00) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL15440804 | 0.80 | HTT (0.67) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL13467765 | 0.79 | POLB (0.65) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL15440670 | 0.75 | POLB (0.60) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL12349851 | 0.75 | ALDH1A1 (0.65) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL15440705 | 0.73 | POLB (0.57) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL10799708 | 0.71 | POLB (0.55) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL7496921 | 0.70 | POLB (0.54) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL12349886 | 0.70 | POLB (0.54) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL10502880 | 0.69 | POLB (0.53) | POLBKMT2AHTTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120308608-A1 | INTERFERON-INDUCING COMPOUNDS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-12-06 | — | — | US | disclosed |
| US-20120308608-A1 | INTERFERON-INDUCING COMPOUNDS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-12-06 | — | — | US | disclosed |
| WO-2011094693-A1 | INTERFERON-INDUCING COMPOUNDS AND USES THEREOF | MOUNT SINAI SCHOOL OF MEDICINE (US) | 2011-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120308608-A1 | INTERFERON-INDUCING COMPOUNDS AND USES THEREOF | IRF3, IFNG, IFNAR1 | POLB 927/4885KMT2A 4305/4885HTT 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.