Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | MITF | O75030 | 1/20 | 1.00 |
| ▸ | DNMT1 | P26358 | 1/20 | 1.00 |
| ▸ | RAD52 | P43351 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349852 | 1.00 | POLB (1.00) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL15440804 | 0.80 | HTT (0.67) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL13467765 | 0.79 | POLB (0.65) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL15440670 | 0.75 | POLB (0.60) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL12349851 | 0.75 | ALDH1A1 (0.65) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL15440705 | 0.73 | POLB (0.57) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL10799708 | 0.71 | POLB (0.55) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL7496921 | 0.70 | POLB (0.54) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL12349886 | 0.70 | POLB (0.54) | POLBKMT2AHTTL3MBTL1NPC1 | |
| SCHEMBL10502880 | 0.69 | POLB (0.53) | POLBKMT2AHTTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116913417-A | DNA-binding small molecule high-throughput screening and characterization method | 四川大学 | 2023-10-20 | — | — | CN | disclosed |