SCHEMBL12350154

SCHEMBL12350154

CC(=O)O/N=C(\CCSc1ccc(Cl)cc1)C(=O)c1ccc(Sc2ccc(C(=O)C(C)(C)C)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ L3MBTL1 Q9Y468 3/20 0.37
▸ SMN1; SMN2 Q16637 3/20 0.35
▸ MAPT P10636 2/20 0.35
▸ HDAC3 O15379 1/20 0.35
▸ HDAC4 P56524 1/20 0.35
▸ HDAC1 Q13547 1/20 0.35
▸ HDAC7 Q8WUI4 1/20 0.35
▸ HDAC2 Q92769 1/20 0.35
▸ HDAC10 Q969S8 1/20 0.35
▸ HDAC11 Q96DB2 1/20 0.35
▸ HDAC8 Q9BY41 1/20 0.35
▸ HDAC6 Q9UBN7 1/20 0.35
▸ HDAC9 Q9UKV0 1/20 0.35
▸ HDAC5 Q9UQL6 1/20 0.35
▸ HPGD P15428 3/20 0.34
▸ RAB9A P51151 2/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12286103 0.93 PKM (0.44) PKMHTTL3MBTL1SMN1; SMN2MAPT
SCHEMBL12455475 0.89 HPGD (0.42) PKMHTTL3MBTL1SMN1; SMN2MAPT
SCHEMBL10144554 0.89 HTT (0.41) PKMHTTL3MBTL1SMN1; SMN2MAPT
SCHEMBL10262989 0.89 HTT (0.41) PKMHTTL3MBTL1SMN1; SMN2MAPT
SCHEMBL17069988 0.89 HTT (0.41) PKMHTTL3MBTL1SMN1; SMN2MAPT
SCHEMBL10203154 0.88 PKM (0.40) PKMHTTL3MBTL1SMN1; SMN2MAPT
SCHEMBL12350150 0.88 HSP90AA1 (0.42) PKMHTTL3MBTL1SMN1; SMN2MAPT
SCHEMBL12522925 0.87 L3MBTL1 (0.48) PKMHTTL3MBTL1SMN1; SMN2MAPT
SCHEMBL2742396 0.86 HTT (0.39) PKMHTTL3MBTL1SMN1; SMN2MAPT
SCHEMBL17069990 0.86 HTT (0.39) PKMHTTL3MBTL1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8835081-B2 Polymerizable composition, color filter, method of producing color filter and solid-state image sensor FUJIFILM CORPORATION (JP) 2014-09-16 — — US disclosed
US-8835081-B2 Polymerizable composition, color filter, method of producing color filter and solid-state image sensor FUJIFILM CORPORATION (JP) 2014-09-16 — — US disclosed
US-8293436-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2012-10-23 — — US disclosed
US-8293436-B2 Oxime derivative, photopolymerizable composition, color filter, and process for producing the same FUJIFILM CORPORATION (JP) 2012-10-23 — — US disclosed
US-20120236426-A1 POLYMERIZABLE COMPOSITION, COLOR FILTER, METHOD OF PRODUCING COLOR FILTER AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2012-09-20 — — US disclosed
US-20120236426-A1 POLYMERIZABLE COMPOSITION, COLOR FILTER, METHOD OF PRODUCING COLOR FILTER AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2012-09-20 — — US disclosed
WO-2011093479-A1 POLYMERIZABLE COMPOSITION, COLOR FILTER, METHOD OF PRODUCING COLOR FILTER AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2011-08-04 — — WO disclosed
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 — — US disclosed
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-04-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100104976-A1 OXIME DERIVATIVE, PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER, AND PROCESS FOR PRODUCING THE SAME PPOX, CYBA, HBB PKM 304/4885HTT 3950/4885L3MBTL1 4829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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