Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12352397 | 0.86 | CACNA2D1 (0.39) | CYP2D6CYP2C9CYP3A4KDM4ECACNA2D1 | |
| SCHEMBL15308365 | 0.83 | CACNA2D1 (0.34) | CYP2D6CYP2C9CYP3A4CACNA2D1MAPT | |
| SCHEMBL12352035 | 0.78 | NPC1 (0.37) | CYP2D6CYP2C9CYP3A4KDM4ECYP19A1 | |
| SCHEMBL2297824 | 0.74 | L3MBTL1 (0.46) | CYP1A2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL12352185 | 0.73 | CACNA2D1 (0.33) | CYP2D6CYP2C9CYP3A4CACNA2D1ALDH1A1 | |
| SCHEMBL12352016 | 0.73 | DHFR (0.49) | CYP2C9CYP1A2CYP2C19LMNAHTT | |
| SCHEMBL2300142 | 0.72 | TSHR (0.38) | CYP2C9CYP3A4CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL2303798 | 0.72 | BCHE (0.39) | CYP19A1SMN1; SMN2L3MBTL1TSHRHTT | |
| SCHEMBL12352015 | 0.70 | LMNA (0.37) | CYP2D6CYP3A4KDM4ECYP19A1CYP1A2 | |
| SCHEMBL15306028 | 0.69 | TSHR (0.40) | CYP2C9CYP3A4CYP1A2CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952025-B2 | Multifunctional radical quenchers and their uses | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130267546-A1 | Multifunctional Radical Quenchers and Their Uses | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Ari (US) | 2013-10-10 | — | — | US | disclosed |
| WO-2011103536-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | ARIZONA BOARD OF REGENTS (US) | 2011-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267546-A1 | Multifunctional Radical Quenchers and Their Uses | SQOR, GSR, GPX4 | CYP2D6 386/4885CYP2C9 1018/4885CYP3A4 452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.