SCHEMBL2844342

SCHEMBL2844342

C=CCOc1cccc(OCCC)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
GPBAR1 Q8TDU6 3/20 0.49
CYSLTR1 Q9Y271 2/20 0.49
TSHR P16473 1/20 0.44
ERN1 O75460 1/20 0.43
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYSLTR2 Q9NS75 1/20 0.41
ALDH1A1 P00352 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP2C19 P33261 1/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2846481 0.91 GPBAR1 (0.50) KMT2AGPBAR1CYSLTR1TSHRMEN1
SCHEMBL1520719 0.87 MEN1 (0.50) KMT2AKDM4EGAAMEN1LMNA
SCHEMBL3388748 0.85 TP53 (0.53) KMT2ATSHRKDM4EGAAMEN1
1-Allyloxy-4-Propoxybenzene SCHEMBL2843517 0.85 CA12 (0.50) KMT2AGAAMEN1LMNAMAPT
1,3-Dipropoxybenzene SCHEMBL73716 0.84 KMT2A (0.63) KMT2AGPBAR1CYSLTR1TSHRKDM4E
SCHEMBL123591 0.81 MAOB (0.53) TSHRKDM4EGAALMNAMAPT
SCHEMBL2842641 0.81 GALR3 (0.46) KMT2AGAAMEN1LMNAMAPT
SCHEMBL22215904 0.81 MEN1 (0.47) KMT2AKDM4EGAAMEN1LMNA
SCHEMBL31267723 0.79 BCHE (0.49) KMT2AKDM4EGAAMEN1ALDH1A1
1-Butyloxy-3-Propoxybenzene SCHEMBL3390925 0.79 TSHR (0.59) KMT2AGPBAR1CYSLTR1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3813804-B1 USE OF DIALKOXYBENZENES FOR CONTROL OF HONEY BEE MITE VARROA DESTRUCTOR UNIV FRASER SIMON (CA) 2026-03-11 EP disclosed
US-11540515-B2 Use of dialkoxybenzenes for control of honey bee mite varroa destructor SIMON FRASER UNIVERSITY (CA) 2023-01-03 US disclosed
US-20180206489-A1 REPELLENT EFFECTIVE AGAINST ANOPHELES GAMBIAE SIMON FRASER UNIVERSITY (CA) 2018-07-26 US disclosed
US-20180206489-A1 REPELLENT EFFECTIVE AGAINST ANOPHELES GAMBIAE SIMON FRASER UNIVERSITY (CA) 2018-07-26 US disclosed
US-20180206489-A1 REPELLENT EFFECTIVE AGAINST ANOPHELES GAMBIAE SIMON FRASER UNIVERSITY (CA) 2018-07-26 US disclosed
US-9497963-B2 Methods and compositions for control of gypsy moth, Lymantria dispar SIMON FRASER UNIVERSITY (CA) 2016-11-22 US disclosed
US-20160152538-A1 REPELLENT EFFECTIVE AGAINST ANOPHELES GAMBIAE SIMON FRASER UNIVERSITY (CA) 2016-06-02 US disclosed
US-20160152538-A1 REPELLENT EFFECTIVE AGAINST ANOPHELES GAMBIAE SIMON FRASER UNIVERSITY (CA) 2016-06-02 US disclosed
US-20160152538-A1 REPELLENT EFFECTIVE AGAINST ANOPHELES GAMBIAE SIMON FRASER UNIVERSITY (CA) 2016-06-02 US disclosed
US-9125406-B2 Methods and compositions for control of cabbage looper, trichoplusia ni SIMON FRASER UNIVERSITY (CA) 2015-09-08 US disclosed
US-20130131185-A1 Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2013-05-23 US disclosed
US-20130045178-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar SIMON FRASER UNIVERSITY (CA) 2013-02-21 US disclosed
US-20100297059-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR SIMON FRASER UNIVERSITY (CA) 2010-11-25 US disclosed
US-20100190865-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar SIMON FRASER UNIVERSITY (CA) 2010-07-29 US disclosed
US-20100160451-A1 METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni SIMON FRASER UNIVERSITY (CA) 2010-06-24 US disclosed
CN-1117291-A 4-Hydroxy-pyran-2-one derivatives for the treatment of retroviral infections UPJOHN CO (US) 1996-02-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130131185-A1 Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni CDV3, ETV1, BOLA2; BOLA2B KMT2A 36/4885GPBAR1 1659/4885CYSLTR1 316/4885
US-20130045178-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar L3MBTL3, L3MBTL4, L3MBTL1 KMT2A 176/4885GPBAR1 362/4885CYSLTR1 18/4885
US-20100190865-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar L3MBTL3, L3MBTL4, L3MBTL1 KMT2A 176/4885GPBAR1 501/4885CYSLTR1 21/4885
US-20180206489-A1 REPELLENT EFFECTIVE AGAINST ANOPHELES GAMBIAE L3MBTL3, PRMT3, PRMT1 KMT2A 1622/4885GPBAR1 741/4885CYSLTR1 810/4885
US-20100160451-A1 METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni CDV3, ETV1, TMSB4X KMT2A 46/4885GPBAR1 1612/4885CYSLTR1 317/4885
US-20100297059-A1 METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR L3MBTL3, L3MBTL4, L3MBTL1 KMT2A 171/4885GPBAR1 511/4885CYSLTR1 21/4885
US-11540515-B2 Use of dialkoxybenzenes for control of honey bee mite varroa destructor API5, DDT, BCL2 KMT2A 160/4885GPBAR1 2483/4885CYSLTR1 3192/4885
US-20160152538-A1 REPELLENT EFFECTIVE AGAINST ANOPHELES GAMBIAE L3MBTL3, PRMT3, PRMT1 KMT2A 1622/4885GPBAR1 741/4885CYSLTR1 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.