Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MLYCD | O95822 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366117 | 0.82 | HDAC1 (0.56) | NPC1RAB9AALDH1A1LMNAPOLB | |
| SCHEMBL15881788 | 0.81 | L3MBTL1 (0.64) | L3MBTL1NPC1RAB9AMLYCDMEN1 | |
| SCHEMBL4501943 | 0.81 | L3MBTL1 (0.64) | L3MBTL1NPC1RAB9AMLYCDMEN1 | |
| SCHEMBL12366208 | 0.81 | SRC (0.57) | RAB9AKMT2AALDH1A1POLB | |
| SCHEMBL13884195 | 0.81 | L3MBTL1 (0.64) | L3MBTL1NPC1RAB9AMLYCDMEN1 | |
| SCHEMBL24713109 | 0.81 | MLYCD (0.67) | L3MBTL1NPC1RAB9AMLYCDMEN1 | |
| SCHEMBL252486 | 0.80 | L3MBTL1 (0.62) | L3MBTL1NPC1RAB9AMLYCDMEN1 | |
| SCHEMBL30661718 | 0.79 | MLYCD (0.65) | L3MBTL1NPC1RAB9AMLYCDMEN1 | |
| SCHEMBL2420380 | 0.79 | L3MBTL1 (0.68) | L3MBTL1NPC1RAB9AMLYCDMEN1 | |
| SCHEMBL249436 | 0.79 | L3MBTL1 (0.61) | L3MBTL1NPC1RAB9AMLYCDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |