Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095012 | 0.83 | SRC (0.61) | SRCRAB9AMAPK1POLBTP53 | |
| SCHEMBL12366093 | 0.82 | MMP13 (0.52) | RAB9APOLBTP53ALDH1A1KDM4E | |
| SCHEMBL12366183 | 0.82 | NPC1 (0.56) | TP53 | |
| SCHEMBL12366113 | 0.81 | L3MBTL1 (0.63) | RAB9APOLBALDH1A1KMT2A | |
| SCHEMBL12366135 | 0.81 | LMNA (0.62) | RAB9APOLBTP53ALDH1A1KMT2A | |
| SCHEMBL11591975 | 0.80 | GAA (0.59) | RAB9AALDH1A1KMT2A | |
| SCHEMBL12366168 | 0.80 | P2RX7 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL5390715 | 0.80 | SRC (0.61) | SRCRAB9AMAPK1POLBTP53 | |
| SCHEMBL28822092 | 0.80 | SRC (0.61) | SRCRAB9AMAPK1POLBTP53 | |
| SCHEMBL4032122 | 0.80 | ALDH1A1 (0.61) | SRCRAB9AMAPK1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |