Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366135 | 0.82 | LMNA (0.62) | LMNAALDH1A1MAOBKMT2A | |
| SCHEMBL12366208 | 0.80 | SRC (0.57) | ALDH1A1KMT2A | |
| SCHEMBL23564760 | 0.79 | P2RX7 (0.46) | P2RX7LMNAPPARGALDH1A1TRPV1 | |
| SCHEMBL31565001 | 0.79 | ALDH1A1 (0.51) | P2RX7LMNAPPARGALDH1A1TRPV1 | |
| SCHEMBL1456923 | 0.79 | P2RX7 (0.49) | P2RX7LMNA | |
| SCHEMBL1456919 | 0.79 | P2RX7 (0.49) | P2RX7LMNA | |
| SCHEMBL12366142 | 0.79 | KMT2A (0.59) | ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL31036978 | 0.79 | P2RX7 (0.49) | P2RX7LMNA | |
| SCHEMBL4038038 | 0.79 | ALDH1A1 (0.51) | P2RX7LMNAPPARGALDH1A1TRPV1 | |
| SCHEMBL12261238 | 0.79 | BDKRB1 (0.40) | P2RX7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |