Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12366497 | 0.94 | SERPINE1 (0.38) | MDM2CLPP | |
| SCHEMBL12366250 | 0.94 | MAPT (0.40) | MDM2 | |
| SCHEMBL12366295 | 0.92 | ITGB1 (0.39) | MDM2 | |
| SCHEMBL12366330 | 0.92 | RGS4 (0.41) | MDM2 | |
| SCHEMBL12366342 | 0.92 | TP53 (0.41) | MDM2 | |
| SCHEMBL12366493 | 0.92 | MDM2 (0.36) | MDM2 | |
| SCHEMBL12366233 | 0.92 | CNR1 (0.42) | MDM2 | |
| SCHEMBL12366364 | 0.91 | GRIN1 (0.39) | MDM2 | |
| SCHEMBL12366746 | 0.91 | PTGS2 (0.36) | MDM2 | |
| SCHEMBL12366335 | 0.91 | LMNA (0.35) | MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998986-B2 | Heterocyclic compounds, in particular N-substituted pyridones for modulating the activity of nuclear receptors | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |