SCHEMBL12366390

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5527733	0.89	KDM4E (0.42)	HTR2CHTR2AHTR2BKCNN4RIPK1
	SCHEMBL12366333	0.87	ALDH1A1 (0.38)	DHFRDCPSHTR2CHTR2AHTR2B
	SCHEMBL15969381	0.82	RIPK1 (0.46)	SLC6A2SLC6A4SLC6A3METAP2HTR2C
	SCHEMBL1013733	0.82	ALDH1A1 (0.39)	SLC6A2SLC6A4SLC6A3HTR2CHTR2A
	SCHEMBL18466652	0.78	MCHR1 (0.50)	SLC6A2SLC6A4SLC6A3METAP2KCNN4
	SCHEMBL5524579	0.77	GPR119 (0.44)	GPR119
	SCHEMBL5525469	0.76	KDM4E (0.46)	IDO1GPR119MCHR1
	SCHEMBL23074226	0.76	RIPK1 (0.41)	SLC6A2SLC6A4SLC6A3METAP2HTR2C
	SCHEMBL21387486	0.76	RIPK1 (0.41)	SLC6A2SLC6A4SLC6A3METAP2DCPS
	SCHEMBL21575503	0.76	TLR9 (0.42)	SLC6A2SLC6A4SLC6A3METAP2DCPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.