Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.60 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12370614 | 0.92 | CTSL (0.64) | CTSLCTSKGRM7CTSBGAA | |
| SCHEMBL12370550 | 0.86 | CTSL (0.66) | CTSLCTSKGRM7CTSBGAA | |
| SCHEMBL12370558 | 0.86 | CTSL (0.68) | CTSLCTSKGRM7CTSBGAA | |
| SCHEMBL12372031 | 0.85 | CTSL (0.58) | CTSLCTSKGRM7CTSBGAA | |
| SCHEMBL12372025 | 0.83 | CTSL (0.71) | CTSLCTSKGRM7CTSBGAA | |
| SCHEMBL12371620 | 0.83 | CTSL (0.55) | CTSLCTSKCTSBGAAMEN1 | |
| SCHEMBL12371583 | 0.83 | CTSL (0.55) | CTSLCTSKCTSBGAAMEN1 | |
| SCHEMBL13619734 | 0.81 | GRM7 (0.50) | CTSLGRM7GAAMEN1KMT2A | |
| SCHEMBL12371439 | 0.81 | CTSL (0.59) | CTSLCTSKCTSBGAAMEN1 | |
| SCHEMBL12370542 | 0.80 | CTSL (0.69) | CTSLCTSKGRM7CTSBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207726-A1 | Inhibitors of Human Cathepsin L, Cathepsin B, and Cathepsin S | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207726-A1 | Inhibitors of Human Cathepsin L, Cathepsin B, and Cathepsin S | CTSB, CTSS, CTSV | CTSL 7/4885CTSK 11/4885GRM7 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.