Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 20/20 | 0.77 |
| ▸ | PDE4A | P27815 | 19/20 | 0.77 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.77 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.77 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698780 | 0.87 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| Sch-351591 SCHEMBL29378661 | 0.86 | PDE4A (0.80) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| Sch-351591 SCHEMBL157018 | 0.86 | PDE4A (0.80) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL13035036 | 0.83 | PDE4B (0.71) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL4699328 | 0.80 | PDE4D (0.69) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL8290205 | 0.78 | PDE4A (0.80) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL7982349 | 0.78 | PDE4B (0.78) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL4703070 | 0.77 | PDE4D (0.75) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL4700531 | 0.77 | PDE4D (0.74) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL7977878 | 0.76 | PDE4A (0.48) | PDE4DPDE4APDE4BPDE4CPDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201665-A1 | Compositions, Methods, and Kits for Treating Influenza Viral Infections | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2011-08-18 | — | — | US | disclosed |
| US-20110028510-A1 | Compositions, Methods, and Kits for Treating Influenza Viral Infections | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201665-A1 | Compositions, Methods, and Kits for Treating Influenza Viral Infections | IL5, CCL5, CCL11 | PDE4D 664/4885PDE4A 336/4885PDE4B 234/4885 |
| US-20110028510-A1 | Compositions, Methods, and Kits for Treating Influenza Viral Infections | IL5, CCL5, CCL11 | PDE4D 664/4885PDE4A 336/4885PDE4B 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.