Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27745045 | 0.98 | THRB (0.37) | THRBCA2ALDH1A1KMT2AHTT | |
| SCHEMBL13292118 | 0.83 | THRB (0.38) | THRBCA2ALDH1A1KMT2AHTT | |
| SCHEMBL8818862 | 0.81 | CA2 (0.39) | CA2ALDH1A1KMT2AHTTLMNA | |
| SCHEMBL12589933 | 0.81 | THRB (0.41) | THRBCA2ALDH1A1KMT2AHTT | |
| SCHEMBL14271158 | 0.81 | THRB (0.41) | THRBCA2ALDH1A1KMT2AHTT | |
| SCHEMBL10617469 | 0.81 | POLB (0.57) | THRBALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8815799 | 0.81 | MAPT (0.40) | THRBCA2ALDH1A1KMT2AHTT | |
| SCHEMBL10700258 | 0.80 | LMNA (0.45) | CA2ALDH1A1KMT2AHTTLMNA | |
| SCHEMBL10787889 | 0.80 | MMP2 (0.47) | CA2ALDH1A1KMT2AHTTLMNA | |
| SCHEMBL8761183 | 0.80 | CA2 (0.50) | THRBCA2ALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9733212-B2 | Sharply resolving labeled protein molecular weight standards | Life Technologies Corporation (US) | 2017-08-15 | — | — | US | disclosed |
| US-8729053-B2 | Nuclear factor kappa B pathway inhibitor composition and use of same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2014-05-20 | — | — | US | disclosed |
| US-20130207044-A1 | Sharply Resolving Labeled Protein Molecular Weight Standards | Life Technologies Corporation (US) | 2013-08-15 | — | — | US | disclosed |
| WO-2013008201-A2 | NOVEL REACTIVE DYES, THERE MIXTURES AND PROCESSES THEREOF | COLOURTEX INDUSTRIES LIMITED (IN) | 2013-01-17 | — | — | WO | disclosed |
| US-20110190240-A1 | NUCLEAR FACTOR KAPPA B PATHWAY INHIBITOR COMPOSITION AND USE OF SAME | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2011-08-04 | — | — | US | disclosed |
| WO-2010033958-A1 | NUCLEAR FACTOR KAPPA B PATHWAY INHIBITOR COMPOSITION AND USE OF SAME | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190240-A1 | NUCLEAR FACTOR KAPPA B PATHWAY INHIBITOR COMPOSITION AND USE OF SAME | RELA, IKBKB, NFKBIA | THRB 2871/4885CA2 336/4885ALDH1A1 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.