Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 11/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374620 | 0.89 | PNP (0.44) | KRASPNPTLR7ADKDOT1L | |
| SCHEMBL12407598 | 0.86 | KRAS (0.46) | KRASPNPTLR7MEN1KMT2A | |
| SCHEMBL12374619 | 0.84 | ADK (0.56) | ADKDOT1L | |
| SCHEMBL12407599 | 0.80 | PNP (0.48) | KRASPNPTLR7MEN1KMT2A | |
| SCHEMBL1737182 | 0.76 | PNP (0.54) | PNPTLR7ADKDOT1LMEN1 | |
| SCHEMBL6729944 | 0.76 | PNP (0.54) | PNPTLR7ADKDOT1LMEN1 | |
| SCHEMBL12150656 | 0.76 | PNP (0.54) | PNPTLR7ADKDOT1LMEN1 | |
| SCHEMBL16198949 | 0.76 | PNP (0.54) | PNPTLR7ADKDOT1LMEN1 | |
| SCHEMBL12154731 | 0.76 | PNP (0.54) | PNPTLR7ADKDOT1LMEN1 | |
| SCHEMBL6727042 | 0.76 | PNP (0.54) | PNPTLR7ADKDOT1LMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003769-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-20100292457-A1 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-7678892-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-03-16 | — | — | US | disclosed |
| US-7678892-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-03-16 | — | — | US | disclosed |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-12-20 | — | — | US | disclosed |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-12-20 | — | — | US | disclosed |
| US-7262029-B2 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292457-A1 | Dye-labeled ribonucleotide triphosphates | DUT, POLRMT, SAMHD1 | KRAS 1231/4885PNP 100/4885TLR7 2657/4885 |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | DUT, POLRMT, SAMHD1 | KRAS 1231/4885PNP 100/4885TLR7 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.