Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 8/20 | 0.56 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | NAE1 | Q13564 | 3/20 | 0.45 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.45 |
| ▸ | UBA1 | P22314 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374617 | 0.88 | ADK (0.62) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL12405887 | 0.86 | ADK (0.52) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL12374621 | 0.84 | KRAS (0.43) | ADKDOT1L | |
| SCHEMBL12405891 | 0.79 | ADK (0.57) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL68465 | 0.75 | PI4KA (0.51) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL13092399 | 0.75 | ADK (0.76) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL16968476 | 0.75 | ADK (0.76) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL16978216 | 0.75 | ADK (0.76) | ADKDOT1LNPC1GALR3S1PR4 | |
| SCHEMBL22327353 | 0.74 | CA2 (0.49) | ADKDOT1LHTTCA2PRMT5 | |
| SCHEMBL21912256 | 0.74 | CA2 (0.49) | ADKDOT1LHTTCA2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003769-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-20100292457-A1 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-7678892-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-03-16 | — | — | US | disclosed |
| US-7678892-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-03-16 | — | — | US | disclosed |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-12-20 | — | — | US | disclosed |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-12-20 | — | — | US | disclosed |
| US-7262029-B2 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292457-A1 | Dye-labeled ribonucleotide triphosphates | DUT, POLRMT, SAMHD1 | ADK 327/4885DOT1L 1277/4885NPC1 2259/4885 |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | DUT, POLRMT, SAMHD1 | ADK 327/4885DOT1L 1277/4885NPC1 2259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.