SCHEMBL12374824

SCHEMBL12374824

C[C@@H]1CO[C@@H]2[C@H]1OC[C@H]2C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12960119 1.00 THRB (0.37) THRBLMNA
SCHEMBL9926385 1.00 THRB (0.37) THRBLMNA
SCHEMBL1066955 1.00 THRB (0.37) THRBLMNA
SCHEMBL12960118 1.00 THRB (0.37) THRBLMNA
SCHEMBL5945027 1.00 THRB (0.37) THRBLMNA
SCHEMBL23348053 1.00 THRB (0.37) THRBLMNA
SCHEMBL13205141 1.00 THRB (0.37) THRBLMNA
SCHEMBL12230286 1.00 THRB (0.37) THRBLMNA
SCHEMBL13182827 1.00 THRB (0.37) THRBLMNA
SCHEMBL12498624 1.00 THRB (0.37) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003811-B2 Nitric oxide donor compounds NICOX S.A. (FR) 2011-08-23 US disclosed
US-20100249189-A1 NITRIC OXIDE DONOR COMPOUNDS NICOX S.A. (FR) 2010-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249189-A1 NITRIC OXIDE DONOR COMPOUNDS NOS3, NOS1, NOS2 THRB 2627/4885LMNA 2520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.