SCHEMBL13205141

SCHEMBL13205141

CC1CO[C@@H]2[C@H](C)CO[C@H]12

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12960119 1.00 THRB (0.37) THRBLMNA
SCHEMBL9926385 1.00 THRB (0.37) THRBLMNA
SCHEMBL1066955 1.00 THRB (0.37) THRBLMNA
SCHEMBL12960118 1.00 THRB (0.37) THRBLMNA
SCHEMBL12374824 1.00 THRB (0.37) THRBLMNA
SCHEMBL5945027 1.00 THRB (0.37) THRBLMNA
SCHEMBL23348053 1.00 THRB (0.37) THRBLMNA
SCHEMBL12230286 1.00 THRB (0.37) THRBLMNA
SCHEMBL13182827 1.00 THRB (0.37) THRBLMNA
SCHEMBL12498624 1.00 THRB (0.37) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8541607-B2 Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses thereof LACER, S.A. (ES) 2013-09-24 US disclosed
US-7777058-B2 Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses thereof LACER S.A. (ES) 2010-08-17 US disclosed
US-20100196387-A1 Disulfide, Sulfide, Sulfoxide, and Sulfone Derivatives of Cyclic Sugars and Uses Thereof LACER, S.A. (ES) 2010-08-05 US disclosed
US-20090169560-A1 DISULFIDE, SULFIDE, SULFOXIDE, AND SULFONE DERIVATIVES OF CYCLIC SUGARS AND USES THEREOF LACER S.A. (ES) 2009-07-02 US disclosed
US-7521571-B2 Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses LACER (ES) 2009-04-21 US disclosed
US-20080161389-A1 METHOD OF TREATING OCULAR HYPERTENSION AND INTESTINAL DISORDERS BY USING DIANHYDROHEXITE MONONITRATE DERIVATIVES LACER, S.A. (ES) 2008-07-03 US disclosed
WO-2007120458-A1 LIQUID CRYSTAL COMPOSITIONS, POLYMER NETWORKS DERIVED THEREFROM AND PROCESS FOR MAKING THE SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-10-25 WO disclosed
US-20070152188-A1 Composition for reducing the transmission of infrared radiation DOW GLOBAL TECHNOLOGIES LLC 2007-07-05 US disclosed
US-20070116945-A1 High strength multilayer laminates comprising twisted nematic liquid crystals DOW GLOBAL TECHNOLOGIES LLC 2007-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090169560-A1 DISULFIDE, SULFIDE, SULFOXIDE, AND SULFONE DERIVATIVES OF CYCLIC SUGARS AND USES THEREOF TST, STS, SORD THRB 1552/4885LMNA 4821/4885
US-20080161389-A1 METHOD OF TREATING OCULAR HYPERTENSION AND INTESTINAL DISORDERS BY USING DIANHYDROHEXITE MONONITRATE DERIVATIVES SI, SLC10A2, ALPI THRB 1930/4885LMNA 2277/4885
US-20100196387-A1 Disulfide, Sulfide, Sulfoxide, and Sulfone Derivatives of Cyclic Sugars and Uses Thereof TST, STS, SORD THRB 1552/4885LMNA 4821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.