SCHEMBL12375094

SCHEMBL12375094

Bc1cc(C2=NCCO2)cc(B)c1B

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
LTA4H P09960 1/20 0.33
KCNN4 O15554 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3794785 0.84 KCNH2 (0.38) KCNH2HRH3LTA4HKCNN4SMN1; SMN2
SCHEMBL7519297 0.75 KCNH2 (0.34) KCNH2HRH3LTA4HSMN1; SMN2
SCHEMBL6670692 0.75 KCNH2 (0.34) KCNH2HRH3LTA4H
SCHEMBL132013 0.75 KCNH2 (0.49) KCNH2HRH3LTA4HKCNN4SMN1; SMN2
SCHEMBL23309639 0.73 KCNH2 (0.33) KCNH2HRH3LTA4H
SCHEMBL105809 0.72 NPC1 (0.41) KCNH2HRH3LTA4HKCNN4SMN1; SMN2
SCHEMBL20410837 0.72 KCNH2 (0.44) KCNH2HRH3LTA4HSMN1; SMN2
SCHEMBL7303946 0.72 LSS (0.33) KCNH2HRH3LTA4HKCNN4SMN1; SMN2
SCHEMBL351341 0.71 ADRA2A (0.39) KCNH2HRH3LTA4HKCNN4SMN1; SMN2
SCHEMBL9700423 0.71 CA1 (0.46) KCNH2HRH3LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8002120-B2 Modified polyamide membrane DOW GLOBAL TECHNOLOGIES LLC (US) 2011-08-23 US disclosed
US-8002120-B2 Modified polyamide membrane DOW GLOBAL TECHNOLOGIES LLC (US) 2011-08-23 US disclosed
US-20110120942-A1 MODIFIED POLYAMIDE MEMBRANE THE DOW CHEMICAL COMPANY 2011-05-26 US disclosed
US-20110120942-A1 MODIFIED POLYAMIDE MEMBRANE THE DOW CHEMICAL COMPANY 2011-05-26 US disclosed
US-7905361-B2 Polyamides modified with oxazoline, thiazoline compounds; overcoating with polyoxazoline or polyoxyethylene glycol; heating; reduced fouling, microbiocides, storage stability DOW GLOBAL TECHNOLOGIES LLC (US) 2011-03-15 US disclosed
US-7905361-B2 Polyamides modified with oxazoline, thiazoline compounds; overcoating with polyoxazoline or polyoxyethylene glycol; heating; reduced fouling, microbiocides, storage stability DOW GLOBAL TECHNOLOGIES LLC (US) 2011-03-15 US disclosed
US-20090194479-A1 MODIFIED POLYAMINE MEMBRANE DOW GLOBAL TECHNOLOGIES LLC 2009-08-06 US disclosed
WO-2008097786-A2 MODIFIED POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES INC. (US) 2008-08-14 WO disclosed
US-20080185332-A1 MODIFIED POLYAMIDE MEMBRANE DOW GLOBAL TECHNOLOGIES INC. (US) 2008-08-07 US disclosed