SCHEMBL12376734

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3870181	0.83	HSD17B10 (0.42)	TSHRPKMRAB9ANPC1NPSR1
	SCHEMBL30226858	0.83	ELANE (0.51)	ELANETSHRPKMRAB9ANPC1
	SCHEMBL15302940	0.83	ELANE (0.51)	ELANETSHRPKMRAB9ANPC1
	SCHEMBL3872104	0.80	TYMS (0.45)	TSHRNPSR1TDP1ALDH1A1SMN1; SMN2
	SCHEMBL3871523	0.80	TSHR (0.33)	TSHRPKMRAB9ANPC1NPSR1
	SCHEMBL3870709	0.80	ELANE (0.36)	ELANETSHRPKMRAB9ANPC1
	SCHEMBL3872145	0.78	ALDH1A1 (0.37)	ELANETSHRALDH1A1SMN1; SMN2GAA
	SCHEMBL30544384	0.77	IDO1 (0.47)	NPC1ALDH1A1SMN1; SMN2KMT2ALMNA
	SCHEMBL15302579	0.77	PLK1 (0.50)	ELANETSHRPKMRAB9ANPC1
	SCHEMBL135116	0.77	IDO1 (0.47)	NPC1ALDH1A1SMN1; SMN2KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.