SCHEMBL12376964

SCHEMBL12376964

COc1ccc(Cc2ccc(OC(=O)c3ccc(Oc4ccc(C(C)=O)cc4)cc3)c(C)c2)cc1C

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.48
MAPT P10636 5/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
GAA P10253 2/20 0.44
SRD5A2 P31213 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12404355 0.98 KMT2A (0.49) KMT2AMAPTHPGDRAB9AL3MBTL1
SCHEMBL19763410 0.98 KMT2A (0.49) KMT2AMAPTHPGDRAB9AL3MBTL1
SCHEMBL12376952 0.94 KMT2A (0.49) KMT2AMAPTL3MBTL1GAATDP1
SCHEMBL12903847 0.93 L3MBTL1 (0.50) KMT2AMAPTHPGDRAB9AL3MBTL1
SCHEMBL14444754 0.93 KMT2A (0.51) KMT2AMAPTL3MBTL1GAATDP1
SCHEMBL15249585 0.90 KMT2A (0.52) KMT2AMAPTHPGDRAB9AL3MBTL1
SCHEMBL12376968 0.88 KMT2A (0.50) KMT2AMAPTHPGDRAB9AGAA
SCHEMBL12404378 0.85 NPC1 (0.46) KMT2AMAPTHPGDRAB9AL3MBTL1
SCHEMBL13324834 0.85 ALDH1A1 (0.44) KMT2AMAPTL3MBTL1GAAALDH1A1
SCHEMBL16573855 0.84 MAPT (0.57) KMT2AMAPTRAB9AL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed