SCHEMBL12376952

SCHEMBL12376952

COc1ccc(Cc2ccc(OC(=O)c3ccc(C(C)=O)cc3)c(C)c2)cc1C

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.49
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
LMNA P02545 1/20 0.44
CA2 P00918 1/20 0.44
MEN1 O00255 2/20 0.43
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
GAA P10253 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TAS2R14 Q9NYV8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14444754 0.94 KMT2A (0.51) KMT2AMAPTL3MBTL1LMNATDP1
SCHEMBL12376964 0.94 KMT2A (0.48) KMT2AMAPTL3MBTL1TDP1GAA
SCHEMBL19763410 0.92 KMT2A (0.49) KMT2AMAPTL3MBTL1TDP1GAA
SCHEMBL12404355 0.92 KMT2A (0.49) KMT2AMAPTL3MBTL1TDP1GAA
SCHEMBL13324834 0.91 ALDH1A1 (0.44) KMT2AMAPTL3MBTL1GAAALDH1A1
SCHEMBL16573855 0.90 MAPT (0.57) KMT2AMAPTL3MBTL1LMNACA2
SCHEMBL16573865 0.88 MEN1 (0.45) KMT2AMAPTL3MBTL1LMNAMEN1
SCHEMBL12903847 0.86 L3MBTL1 (0.50) KMT2AMAPTL3MBTL1LMNAMEN1
SCHEMBL12677698 0.86 ALDH1A1 (0.47) KMT2AMAPTL3MBTL1LMNAGAA
SCHEMBL12799825 0.84 TAS1R3 (0.43) KMT2AMAPTL3MBTL1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9746816-B2 Image forming apparatus and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2017-08-29 US disclosed
US-20170205719-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US disclosed
US-9703215-B2 Electrophotographic photoreceptor, method of producing same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2017-07-11 US disclosed
US-20160161870-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PRODUCING SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2016-06-09 US disclosed
US-20110206411-A1 IMAGE FORMING APPARATUS AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2011-08-25 US disclosed
US-7985522-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-26 US disclosed
US-20110013934-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2011-01-20 US disclosed
US-7604913-B2 Electrophotographic photosensitive body MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-20 US disclosed
US-20090047589-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-19 US disclosed
US-20080063963-A1 Electrophotographic Photosensitive Body MITSUBISHI CHEMICAL CORPORATION (JP) 2008-03-13 US disclosed
US-7244535-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2007-07-17 US disclosed