Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.63 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | F2R | P25116 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15985297 | 0.87 | NLRP3 (0.59) | NLRP3MAPTALDH1A1MAPK1F2R | |
| SCHEMBL21788534 | 0.84 | RAB9A (0.56) | RAB9APOLBNR4A1NLRP3GAA | |
| SCHEMBL10970617 | 0.84 | RAB9A (0.85) | RAB9APOLBNR4A1GAAKMT2A | |
| SCHEMBL12377475 | 0.83 | CA1 (0.60) | RAB9APOLBNR4A1NLRP3KMT2A | |
| SCHEMBL14756770 | 0.83 | NLRP3 (0.58) | RAB9APOLBNR4A1NLRP3GAA | |
| SCHEMBL7744399 | 0.83 | NLRP3 (0.58) | RAB9APOLBNR4A1NLRP3GAA | |
| SCHEMBL8622297 | 0.83 | NLRP3 (0.58) | RAB9APOLBNLRP3KMT2AMEN1 | |
| SCHEMBL23169416 | 0.83 | LMNA (0.58) | RAB9APOLBNLRP3KMT2AMEN1 | |
| SCHEMBL6332545 | 0.83 | KMT2A (0.68) | RAB9APOLBNLRP3GAAKMT2A | |
| SCHEMBL20605366 | 0.83 | NLRP3 (0.65) | NLRP3KMT2AMEN1L3MBTL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230134116-A1 | CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS | PROTOMER TECHNOLOGIES, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20230134116-A1 | CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS | PROTOMER TECHNOLOGIES, INC. | 2023-05-04 | — | — | US | disclosed |
| US-20210369815-A1 | GLUCOSE RESPONSIVE INSULINS | PROTOMER TECHNOLOGIES, INC. | 2021-12-02 | — | — | US | disclosed |
| US-11052133-B2 | Glucose responsive insulins | PROTOMER TECHNOLOGIES, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| US-20200268291-A1 | MEDIATION OF IN VIVO ANALYTE SIGNAL DEGRADATION | SENSEONICS, INCORPORATED (US) | 2020-08-27 | — | — | US | disclosed |
| US-10683379-B2 | Polymers, hydrogels, and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-06-16 | — | — | US | disclosed |
| WO-2020045342-A1 | PRETREATMENT REAGENT, AND NANOPARTICLE ANALYSIS AND RECOVERY METHOD | 国立大学法人東京大学 | 2020-03-05 | — | — | WO | disclosed |
| US-20190329187-A1 | AFFINITY POLYMERS AND METHODS FOR REDUCING PURINE LEVELS IN COMPLEX MIXTURES | NITTO DENKO CORPORATION (JP) | 2019-10-31 | — | — | US | disclosed |
| US-20190247468-A1 | GLUCOSE RESPONSIVE INSULINS | PROTOMER TECHNOLOGIES, INC. | 2019-08-15 | — | — | US | disclosed |
| US-9732101-B2 | Bioreversible boronates for delivery of molecules into cells | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-08-15 | — | — | US | disclosed |
| US-20160083706-A1 | BORONATE-MEDIATED DELIVERY OF MOLECULES INTO CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-24 | — | — | US | disclosed |
| US-20160024122-A1 | BIOREVERSIBLE BORONATES FOR DELIVERY OF MOLECULES INTO CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-28 | — | — | US | disclosed |
| US-9234048-B2 | Boronate-mediated delivery of molecules into cells | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-01-12 | — | — | US | disclosed |
| WO-2015106292-A1 | BCR-ABL TYROSINE-KINASE LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| WO-2015081280-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |
| US-20140243286-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2014-08-28 | — | — | US | disclosed |
| US-20130196433-A1 | Boronate-Mediated Delivery of Molecules into Cells | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-08-01 | — | — | US | disclosed |
| WO-2013033270-A2 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| US-6919382-B2 | Preparation and uses of conjugated solid supports for boronic acids | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2005-07-19 | — | — | US | disclosed |
| US-20030044840-A1 | Preparation and uses of conjugated solid supports for boronic acids | GOVERNORS OF THE UNIVERSITY OF ALBERTA, THE (CA) | 2003-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11052133-B2 | Glucose responsive insulins | GLP1R, GPR119, IAPP | RAB9A 3133/4885POLB 4856/4885NR4A1 1106/4885 |
| US-20190247468-A1 | GLUCOSE RESPONSIVE INSULINS | GLP1R, GPR119, IAPP | RAB9A 3133/4885POLB 4856/4885NR4A1 1106/4885 |
| US-10683379-B2 | Polymers, hydrogels, and uses thereof | BOLA2; BOLA2B, PARG, BRAP | RAB9A 2827/4885POLB 1465/4885NR4A1 3516/4885 |
| US-20200268291-A1 | MEDIATION OF IN VIVO ANALYTE SIGNAL DEGRADATION | SLC2A1, SLC2A4, SLC2A3 | RAB9A 4008/4885POLB 4764/4885NR4A1 2392/4885 |
| US-20140243286-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | BRDT, BRD4, BRD1 | RAB9A 4123/4885POLB 1252/4885NR4A1 832/4885 |
| US-20030044840-A1 | Preparation and uses of conjugated solid supports for boronic acids | SLC43A1, SBDS, SLC7A5 | RAB9A 2477/4885POLB 613/4885NR4A1 2015/4885 |
| US-20160024122-A1 | BIOREVERSIBLE BORONATES FOR DELIVERY OF MOLECULES INTO CELLS | BAG6, BCAP31, PHB1 | RAB9A 341/4885POLB 1552/4885NR4A1 4050/4885 |
| US-20230134116-A1 | CONJUGATES FOR SELECTIVE RESPONSIVENESS TO VICINAL DIOLS | GPR119, GLP1R, IAPP | RAB9A 3213/4885POLB 4793/4885NR4A1 3691/4885 |
| US-20130196433-A1 | Boronate-Mediated Delivery of Molecules into Cells | BCAP31, PHAX, BTD | RAB9A 1908/4885POLB 1971/4885NR4A1 3859/4885 |
| US-20210369815-A1 | GLUCOSE RESPONSIVE INSULINS | GLP1R, GPR119, IAPP | RAB9A 3133/4885POLB 4856/4885NR4A1 1106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.