Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377596 | 0.74 | MTNR1A (0.33) | ALDH1A1MTNR1AMTNR1BMAPT | |
| SCHEMBL8773436 | 0.73 | CYP1A2 (0.43) | ALDH1A1CYP1A2KDM4EMEN1HPGD | |
| SCHEMBL12422795 | 0.72 | ALDH1A1 (0.40) | ALDH1A1NPSR1MTNR1AMTNR1BCES1 | |
| SCHEMBL12422791 | 0.71 | G6PC1 (0.43) | ALDH1A1MEN1KMT2ATSHRSIGMAR1 | |
| SCHEMBL28005546 | 0.69 | SIGMAR1 (0.38) | ALDH1A1L3MBTL1MTNR1AMTNR1BCES1 | |
| SCHEMBL12377627 | 0.68 | ALDH1A1 (0.40) | ALDH1A1CYP2C19CYP1A2CYP2C9NPSR1 | |
| SCHEMBL12422812 | 0.68 | SIGMAR1 (0.51) | TDP1CYP2C19CYP1A2CYP2C9KDM4E | |
| SCHEMBL28005578 | 0.68 | AOC3 (0.41) | ALDH1A1MAPK1TDP1CYP2C19CYP1A2 | |
| SCHEMBL24358840 | 0.67 | MTNR1A (0.50) | ALDH1A1MAPK1TDP1CYP2C19CYP1A2 | |
| SCHEMBL12422828 | 0.67 | HDAC1 (0.42) | MTNR1AMTNR1BCHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003287-B2 | Low temperature charge transportability and potential, sensitivity and photoresponsiveness; durability | SHARP KABUSHIKI KAISHA (JP) | 2011-08-23 | — | — | US | disclosed |
| US-20080166642-A1 | Electrophotographic photoconductor and image-forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2008-07-10 | — | — | US | disclosed |