Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.53 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622481 | 1.00 | TSHR (0.53) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL10308367 | 0.87 | GABRP (0.35) | TP53HCAR2ALDH1A1GAAGABRP | |
| SCHEMBL10308366 | 0.87 | GABRP (0.35) | TP53HCAR2ALDH1A1GAAGABRP | |
| Maleic Acid SCHEMBL28723595 | 0.81 | TSHR (0.60) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL8132724 | 0.81 | TSHR (0.60) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Fumaric Acid SCHEMBL8132728 | 0.81 | TSHR (0.60) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL10942826 | 0.80 | TSHR (0.50) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL19976103 | 0.80 | TSHR (0.50) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL25665585 | 0.78 | GABRP (0.32) | TP53HCAR2ALDH1A1GAAGABRP | |
| SCHEMBL1413242 | 0.78 | TSHR (0.47) | TSHRTP53EGLN1EGLN3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649325-B2 | Actinically-crosslinkable polysiloxane-polyglycerol block copolymers and methods of making and use thereof | Clearlab Sg Pte Ltd. (SG) | 2023-05-16 | — | — | US | disclosed |
| US-9921230-B2 | Methods for diagnosis and treatment of concussion or brain injury | RHODE ISLAND HOSPITAL (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170363637-A1 | Method and Kit for Determining Risk of Preterm Birth and/or Birth of Low-Birth-Weight Baby | HIROSHIMA UNIVERSITY (JP) | 2017-12-21 | — | — | US | disclosed |
| US-20160103140-A1 | Methods for Diagnosis and Treatment of Concussion or Brain Injury | RHODE ISLAND HOSPITAL | 2016-04-14 | — | — | US | disclosed |
| US-8969303-B2 | Tocotrienol esters | FIRST TECH INTERNATIONAL LIMITED (CN) | 2015-03-03 | — | — | US | disclosed |
| US-20110196030-A1 | TOCOTRIENOL ESTERS | FIRST TECH INTERNATIONAL LIMITED (CN) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170363637-A1 | Method and Kit for Determining Risk of Preterm Birth and/or Birth of Low-Birth-Weight Baby | LGALS3, LGALS3BP, LGALS1 | TSHR 2759/4885TP53 4398/4885EGLN1 2964/4885 |
| US-20110196030-A1 | TOCOTRIENOL ESTERS | TTPA, MBOAT1, TBXAS1 | TSHR 635/4885TP53 4311/4885EGLN1 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.