Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279656 | 0.85 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL30480313 | 0.79 | RAB9A (0.57) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL10389918 | 0.78 | MAP4K4 (0.59) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL4958273 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL8377993 | 0.78 | TDP1 (0.65) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| Sulfuric Acid SCHEMBL28400618 | 0.76 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL42942 | 0.76 | CA12 (0.64) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL29902348 | 0.76 | CA12 (0.58) | ALDH1A1KMT2AMEN1TDP1CREBBP | |
| SCHEMBL2642425 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 | |
| SCHEMBL29639739 | 0.76 | PARP1 (0.65) | ALDH1A1KMT2AMEN1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110206605-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | KYOTO UNIVERSITY (JP) | 2011-08-25 | — | — | US | disclosed |
| US-20110081663-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | KYOTO UNIVERSITY (JP) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206605-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | IAPP, NGLY1, GPR119 | ALDH1A1 4779/4885KMT2A 1068/4885MEN1 338/4885 |
| US-20110081663-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | IAPP, GPR119, NPY1R | ALDH1A1 3077/4885KMT2A 1215/4885MEN1 1340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.