Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725929 | 0.83 | SPHK2 (0.47) | GAAKMT2AHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL47363 | 0.79 | CA1 (0.57) | KMT2AALDH1A1L3MBTL1MEN1 | |
| SCHEMBL15504664 | 0.79 | SMN1; SMN2 (0.57) | GAAKMT2AHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL18377765 | 0.79 | L3MBTL1 (0.68) | GAAKMT2ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12377935 | 0.79 | GAA (0.46) | GAAKMT2AHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL18376133 | 0.77 | CFD (0.64) | SMN1; SMN2KDM4EALDH1A1CFDHDAC2 | |
| SCHEMBL948542 | 0.77 | GAA (0.68) | GAAHSD17B10SMN1; SMN2ALDH1A1HDAC2 | |
| SCHEMBL17018687 | 0.75 | SLC1A2 (0.41) | GAAKMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL285298 | 0.72 | SMN1; SMN2 (0.62) | GAAKMT2AHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL14725933 | 0.71 | FURIN (0.40) | GAAKMT2AHSD17B10SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110206605-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | KYOTO UNIVERSITY (JP) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110206605-A1 | Molecular Probe for Imaging of Pancreatic Islets and Use of the Same | IAPP, NGLY1, GPR119 | GAA 996/4885KMT2A 1068/4885HSD17B10 4300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.