Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377937 | 0.83 | GAA (0.46) | GAAKMT2AHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL8298056 | 0.81 | KDM4E (0.53) | SPHK2KDM1AMRGPRX4GAAKMT2A | |
| SCHEMBL23714782 | 0.80 | HDAC8 (0.59) | KMT2ASMN1; SMN2L3MBTL1CA1CA2 | |
| SCHEMBL13331944 | 0.80 | PARP1 (0.58) | KMT2AALDH1A1CA1CA2 | |
| SCHEMBL14725927 | 0.80 | TP53BP1 (0.54) | SPHK2KDM1AMRGPRX4GAAKMT2A | |
| SCHEMBL3090568 | 0.78 | GAA (0.63) | SPHK2GAAHSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL13501434 | 0.76 | ACHE (0.53) | SPHK2MRGPRX4GAAKMT2AHSD17B10 | |
| SCHEMBL7641409 | 0.76 | POLB (0.65) | MRGPRX4ALDH1A1L3MBTL1 | |
| SCHEMBL8298064 | 0.75 | TSHR (0.62) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1PRSS1 | |
| SCHEMBL7343748 | 0.75 | MEN1 (0.46) | SPHK2GAAKMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130052132-A1 | Method for Producing Radioactively Labeled Polypeptide | ARKRAY, INC. (JP) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130052132-A1 | Method for Producing Radioactively Labeled Polypeptide | XPNPEP2, ARGLU1, XPNPEP1 | SPHK2 3840/4885KDM1A 1765/4885MRGPRX4 1323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.