SCHEMBL12379224

SCHEMBL12379224

CC1(C)c2ccccc2-c2ccc(N(c3ccc4c(c3)C(C)(C)c3ccccc3-4)c3cccc4ccccc34)cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.37
PDK2 Q15119 3/20 0.37
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPK1 P28482 1/20 0.35
SLC6A2 P23975 2/20 0.33
MLNR O43193 1/20 0.33
NR1I2 O75469 1/20 0.33
CHRM2 P08172 1/20 0.33
ADRB1 P08588 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
CHRM3 P20309 1/20 0.33
DRD1 P21728 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15178615 0.99 SIGMAR1 (0.36) SIGMAR1PDK2MEN1KMT2AMAPT
SCHEMBL15138214 0.96 SIGMAR1 (0.38) SIGMAR1PDK2MEN1KMT2AMAPT
SCHEMBL20842770 0.96 SIGMAR1 (0.35) SIGMAR1PDK2MEN1KMT2AMAPT
SCHEMBL13986638 0.96 SIGMAR1 (0.38) SIGMAR1PDK2MEN1KMT2AMAPT
SCHEMBL6373507 0.95 PDK2 (0.34) SIGMAR1PDK2MEN1KMT2AMAPT
SCHEMBL20066627 0.95 SIGMAR1 (0.34) SIGMAR1PDK2MEN1KMT2AMAPT
SCHEMBL808074 0.95 SIGMAR1 (0.34) SIGMAR1PDK2MEN1KMT2AMAPT
SCHEMBL22936727 0.95 SIGMAR1 (0.37) SIGMAR1PDK2MEN1KMT2AMAPT
SCHEMBL15138688 0.95 SIGMAR1 (0.37) SIGMAR1PDK2MEN1KMT2AMAPT
SCHEMBL3870811 0.94 SIGMAR1 (0.39) SIGMAR1PDK2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 US disclosed
US-8691398-B2 4-aminofluorene compound and organic light emitting device CANON KABUSHIKI KAISHA (JP) 2014-04-08 US disclosed
US-8691398-B2 4-aminofluorene compound and organic light emitting device CANON KABUSHIKI KAISHA (JP) 2014-04-08 US disclosed
US-8288018-B2 Amino compound for organic light-emitting device and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2012-10-16 US disclosed
US-8288018-B2 Amino compound for organic light-emitting device and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2012-10-16 US disclosed
US-20110198576-A1 AMINO COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-08-18 US disclosed
US-20110198576-A1 AMINO COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2011-08-18 US disclosed
US-7960039-B2 Amino compound for organic light-emitting device and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2011-06-14 US disclosed
US-7960039-B2 Amino compound for organic light-emitting device and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2011-06-14 US disclosed
US-20100033081-A1 4-AMINOFLUORENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2010-02-11 US disclosed
US-20100033081-A1 4-AMINOFLUORENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2010-02-11 US disclosed
US-20070228941-A1 AMINO COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2007-10-04 US disclosed
US-20070228941-A1 AMINO COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877509-B2 Organic light-emitting element CRY1, CRY2, NR2E3 SIGMAR1 2356/4885PDK2 3759/4885MEN1 1414/4885
US-20100033081-A1 4-AMINOFLUORENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE ALAD, CYP4F12, CYP4F11 SIGMAR1 3164/4885PDK2 2280/4885MEN1 1535/4885
US-20070228941-A1 AMINO COMPOUND FOR ORGANIC LIGHT-EMITTING DEVICE AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME ARL1, APOL1, UFL1 SIGMAR1 1223/4885PDK2 2514/4885MEN1 1138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.